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HYOU1 Antikörper (Biotin)

HYOU1 Reaktivität: Human WB, IF, ICC Wirt: Maus Monoclonal 6E3-2C3 Biotin
Produktnummer ABIN2868639
  • Target Alle HYOU1 Antikörper anzeigen
    HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
    Reaktivität
    • 66
    • 26
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 46
    • 20
    Maus
    Klonalität
    • 42
    • 25
    Monoklonal
    Konjugat
    • 24
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HYOU1 Antikörper ist konjugiert mit Biotin
    Applikation
    • 52
    • 17
    • 14
    • 13
    • 13
    • 12
    • 11
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Detects ~170 kDa.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Protein G Purified
    Immunogen
    Recombinant Full length GRP170 Protein
    Klon
    6E3-2C3
    Isotyp
    IgG2b
    Top Product
    Discover our top product HYOU1 Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    1 μg/ml of ABIN2868639 was sufficient for detection of GRP170 in 20 μg of HEK293 lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    HYOU1 (Hypoxia Up Regulated 1 (HYOU1))
    Andere Bezeichnung
    GRP170 (HYOU1 Produkte)
    Synonyme
    GRP-170 antikoerper, Grp170 antikoerper, HSP12A antikoerper, ORP-150 antikoerper, ORP150 antikoerper, AI415631 antikoerper, CBP-140 antikoerper, Cab140 antikoerper, Orp150 antikoerper, id:ibd5056 antikoerper, wu:fd14c05 antikoerper, zgc:56019 antikoerper, HYOU1 antikoerper, orp150 antikoerper, GRP170 antikoerper, hypoxia up-regulated 1 antikoerper, hypoxia up-regulated protein 1 antikoerper, hypoxia up-regulated 1 S homeolog antikoerper, HYOU1 antikoerper, Hyou1 antikoerper, hyou1 antikoerper, LOC100380749 antikoerper, hyou1.S antikoerper
    Hintergrund
    GRP170, also known as ORP150, is the largest member of glucose-regulated Antibodys, and acts as a human chaperone Antibody. It is thought to play an important role in Antibody folding and secretion in the ER. Suppression of the Antibody is associated with accelerated apoptosis, therefore having an important cryoprotective role in hypoxia-induced cellular pertubation. This cryopotective role has led to an anti-tumor immune response, which will hopefully lead to therapeutic immunizations against cancers (1). GRP170 has also been shown to bind with dendritic cells and provide the danger signals to induce anti-tumor immune responses (2).
    Gen-ID
    10525
    NCBI Accession
    NP_006389
    UniProt
    Q9Y4L1
    Pathways
    ER-Nucleus Signaling, SARS-CoV-2 Protein Interaktom
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