PP5 Antikörper (APC)
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- Target Alle PP5 (PPP5C) Antikörper anzeigen
- PP5 (PPP5C) (Protein Phosphatase 5, Catalytic Subunit (PPP5C))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser PP5 Antikörper ist konjugiert mit APC
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Applikation
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- Detects ~58 kDa.
- Kreuzreaktivität
- Human
- Aufreinigung
- Protein G Purified
- Immunogen
- Full length human PP5 protein
- Klon
- 12F7
- Isotyp
- IgG1
- Top Product
- Discover our top product PPP5C Primärantikörper
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- Applikationshinweise
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
- Kommentare
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1 μg/ml of ABIN2868710 was sufficient for detection of PP5 in 15 μg of human A431 lysates by ECL analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- Target
- PP5 (PPP5C) (Protein Phosphatase 5, Catalytic Subunit (PPP5C))
- Andere Bezeichnung
- PP5 (PPP5C Produkte)
- Hintergrund
- Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues, potentially playing a role in the regulation of cell growth and differentiation. PP5 or PPT is predominantly a nuclear protein and interacts with CDC16 and CDC27. It is found in association with several proteins that influence intracellular signlaing-cascades intitiated by hormones (glucocorticoids) or cellular stress (hypoxia, oxidative stress and DNA Damage). It phosphorylates serine residues of skeletal muscle phosphorylase and histone H1. It may also be involved in mitosis and RNA biogenesis regulation (1,2).
- Gen-ID
- 5536
- NCBI Accession
- NP_006238
- UniProt
- P53041
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