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UVRAG Antikörper (APC)

UVRAG Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal APC
Produktnummer ABIN2868820
  • Target Alle UVRAG Antikörper anzeigen
    UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
    Reaktivität
    • 64
    • 37
    • 29
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 60
    • 4
    Kaninchen
    Klonalität
    • 62
    • 2
    Polyklonal
    Konjugat
    • 26
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UVRAG Antikörper ist konjugiert mit APC
    Applikation
    • 58
    • 23
    • 13
    • 12
    • 12
    • 12
    • 9
    • 8
    • 6
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Spezifität
    Predicted molecular weight at ~78.1 kDa. Observed molecular weights in the 75-90 kDa range.
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Peptide Affinity Purified
    Immunogen
    Synthetic peptide from the mid-protein of human UVRAG
    Top Product
    Discover our top product UVRAG Primärantikörper
  • Applikationshinweise
    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    Kommentare

    A 1:1000 dilution of ABIN2868820 was sufficient for detection of UVRAG on HeLa cell lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Conjugated antibodies should be stored at 4°C
  • Target
    UVRAG (UV Radiation Resistance Associated Gene (UVRAG))
    Andere Bezeichnung
    UVRAG (UVRAG Produkte)
    Hintergrund
    UVRAG (UV radiation resistance-associated gene) is associated with the Beclin-1/PI3KC3 complex and promotes PI3KC3 enzymatic activity and autophagy, while suppressing proliferation (1). Beclin-1 binding to UVRAG promotes both autophagosome maturation and endocytic trafficking (2). UVRAG is also a potential tumor suppressor protein with frameshift mutations observed in colon and gastric carcinomas (3-4). It is highly expressed in the brain, lung, kidney and liver.
    Gen-ID
    7405
    NCBI Accession
    NP_003360
    UniProt
    Q9P2Y5
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