Mannose Receptor Antikörper

Produktnummer ABIN291690

Produktdetails anti-Mannose Receptor Antikörper

Target: Mannose Receptor (MR)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Mannose Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: Specific for human CD206, otherwise known as macrophage mannose receptor (MMR), a transmembrane protein and member of the multilectin family of pattern recognition receptors (PRRs), which mediates phagocytosis and endocytosis, and is modulated by a range of factors including cytokines, immunoglobulin receptors and pathogens. CD206 has two extracellular lectin binding sites: the cysteine-rich domain binds to sulphated sugars of glycoproteins such as thyroid stimulating hormone, whilst the recognition of mannose and fucose occurs through carbohydrate recognition domains (CRDs). The widespread distribution and recognition of a wide range of antigens by macrophages, plays a key role in both innate and adaptive immunity, with CD206 able to bind to both gram-negative and gram-positive bacteria, mycobacterium, yeasts, fungi and parasites.

Aufreinigung: Affinity purified

Immunogen: Monocyte-derived dendritic cells.

Type of Immunogen: Cells

Klon: 7-450

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-Fr (1:50 - 1:500)

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Short term: -20°C
Long term: -20°C.

Details zu Mannose Receptor

Target: Mannose Receptor (MR)

Andere Bezeichnung: Mannose Receptor / CD206 (MR Produkte)

Synonyme: CD206 antikoerper, CLEC13D antikoerper, CLEC13DL antikoerper, MMR antikoerper, MRC1L1 antikoerper, bA541I19.1 antikoerper, AW259686 antikoerper, MR antikoerper, mannose receptor C-type 1 antikoerper, mannose receptor, C type 1 antikoerper, MRC1 antikoerper, Mrc1 antikoerper

Hintergrund: Name/Gene ID: MRC1

Synonyms: MRC1, BA541I19.1, CLEC13D, CD206, CD206 antigen, Macrophage mannose receptor 1, Mannose Receptor, Macrophage mannose receptor, MMR, Mannose receptor, C type 1, MRC1L1, CLEC13DL

Gen-ID: 4360