CXCR4 Antikörper
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- Target Alle CXCR4 Antikörper anzeigen
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
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Reaktivität
- Human, Non-Human Primate
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CXCR4 Antikörper ist unkonjugiert
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Applikation
- Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Spezifität
- The mouse monoclonal antibody 12G5 recognizes an extracellular epitope of CD184, a 45 kDa G-protein-linked CXC chemokine receptor widely expressed on blood and tissue cells.
- Kreuzreaktivität (Details)
- Human, Non-Human Primates
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- CP-MAC-infected Sup-T1 cells
- Klon
- 12G5
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product CXCR4 Primärantikörper
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anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 201-294) antibody
CXCR4 Reaktivität: Human, Maus, Ratte, Kaninchen WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-46) antibodyCXCR4 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2G9 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 262-352) antibodyCXCR4 Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (N-Term) antibodyCXCR4 Reaktivität: Human, Maus, Kaninchen, Schwein, Pferd WB, IHC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 14-40) antibodyCXCR4 Reaktivität: Human, Maus WB, ELISA, IHC, IHC (p) Wirt: Ziege Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-356) antibodyCXCR4 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) antibody (PE)CXCR4 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal 12G5 PE
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 1-46) antibodyCXCR4 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1F8 unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (C-Term) antibodyCXCR4 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (AA 2-15), (Extracellular), (N-Term) antibodyCXCR4 Reaktivität: Human, Maus, Ratte WB, IHC, FACS, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Flow cytometry: Recommended dilution: 2-4 μg/mL.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- Target
- CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
- Andere Bezeichnung
- CD184 / CXCR4 (CXCR4 Produkte)
- Hintergrund
- C-X-C motif chemokine receptor 4,CD184, also known as CXCR4 or fusin, is a receptor for the C-X-C chemokine SDF-1. It is expressed mainly in hematopoietic cells, vascular endothelium, and neural tissue. CD184 is a G-protein coupled receptor containing extracellular N-terminal, seven transmembrane domains and intracellular C-terminal domain. It transduces signal by increasing the intracellular calcium level. CD184 plays an essential role in vascularization of the gastrointestinal tract, and is involved in cerebellar development and in hematopoiesis. It is also a coreceptor (with CD4) for HIV-1 X4 virus and a primary receptor for some HIV-2 isolates.,CXCR4, LAP3, LCR1, HM89, fusin, SDF1R
- Gen-ID
- 7852
- UniProt
- P61073
- Pathways
- Regulation of Cell Size, CXCR4-mediated Signaling Events
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