IKZF1 Antikörper (C-Term) (PE)

Produktnummer ABIN2967182

Produktdetails anti-IKZF1 Antikörper (PE)

Target: IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IKZF1 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Spezifität: The mouse monoclonal antibody 4E9 recognizes Ikaros, a transcription factor (intracellular antigen) expressed broadly in hematopoietic progenitors and serving as a key regulator of lymphopoiesis.

Kreuzreaktivität (Details): Human, Mouse

Aufreinigung: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Recombinant human Ikaros (C-terminal part)

Klon: 4E9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Intracellular staining.

Kommentare:

The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Details zu IKZF1

Target: IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Andere Bezeichnung: Ikaros (IKZF1 Produkte)

Synonyme: Hs.54452 antikoerper, IK1 antikoerper, IKAROS antikoerper, LYF1 antikoerper, PRO0758 antikoerper, ZNFN1A1 antikoerper, hIk-1 antikoerper, RGD1562979 antikoerper, ikaros antikoerper, znfn1a1 antikoerper, ik1 antikoerper, lyf1 antikoerper, hik-1 antikoerper, pro0758 antikoerper, hs.54452 antikoerper, MGC108252 antikoerper, 5832432G11Rik antikoerper, Ikaros antikoerper, LyF-1 antikoerper, Zfpn1a1 antikoerper, Znfn1a1 antikoerper, hlk-1 antikoerper, mKIAA4227 antikoerper, ikzf1 antikoerper, IKAROS family zinc finger 1 antikoerper, IKAROS family zinc finger 1 (Ikaros) antikoerper, IKZF1 antikoerper, Ikzf1 antikoerper, ikzf1 antikoerper

Hintergrund: IKAROS family zinc finger 1,Ikaros, also known as IKZF1 (Ikaros family zinc finger protein 1) is a hematopoietic-specific transcription factor involved in the regulation of lymphocyte development, together with other members of this family, such as Aiolos and Helios. Ikaros forms homo- and heterodimers with these proteins and functions predominantly in early hematopoietic development. Expression of Ikaros, Aiolos and Helios is restricted to cells of the hematopoietic system, whereas other family members, Eos and Pegassus, are more widely expressed. Disruption of Ikaros leads to T and B cell leukemias.,IKZF1, IK1, LYF1, LyF-1, IKAROS, PPP1R92, PRO0758, ZNFN1A1, Hs.54452, IKAROS family zinc finger 1, Lymphoid transcription factor LyF-1

Gen-ID: 10320

UniProt: Q13422

Pathways: Production of Molecular Mediator of Immune Response