PITX2 Antikörper (AA 1-100)

Produktnummer ABIN3015652

Produktdetails anti-PITX2 Antikörper

Target: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PITX2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MNCMKGPLHL EHRAAGTKLS AVSSSSCHHP QPLAMASVLA PGQPRSLDSS KHRLEVHTIS DTSSPEAAEK DKSQQGKNED VGAEDPSKKK RQRRQRTHFT

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human PITX2 (NP_000316.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PITX2

Target: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Andere Bezeichnung: PITX2 (PITX2 Produkte)

Synonyme: ARP1 antikoerper, Brx1 antikoerper, IDG2 antikoerper, IGDS antikoerper, IGDS2 antikoerper, IHG2 antikoerper, IRID2 antikoerper, Otlx2 antikoerper, PTX2 antikoerper, RGS antikoerper, RIEG antikoerper, RIEG1 antikoerper, RS antikoerper, 9430085M16Rik antikoerper, Brx1a antikoerper, Brx1b antikoerper, Munc30 antikoerper, Pitx2a antikoerper, Pitx2b antikoerper, Pitx2c antikoerper, Pitx2cbeta antikoerper, Ptx2 antikoerper, Rieg antikoerper, pitx2a antikoerper, pitx2c antikoerper, zgc:110508 antikoerper, XPtx2b antikoerper, xPtx2 antikoerper, xpitx2 antikoerper, arp1 antikoerper, brx1 antikoerper, idg2 antikoerper, igds antikoerper, igds2 antikoerper, ihg2 antikoerper, irid2 antikoerper, otlx2 antikoerper, pitx2-A antikoerper, ptx2 antikoerper, rgs antikoerper, rieg antikoerper, rieg1 antikoerper, pitx-2 antikoerper, pitx2 antikoerper, paired like homeodomain 2 antikoerper, paired-like homeodomain transcription factor 2 antikoerper, paired-like homeodomain 2 antikoerper, paired like homeodomain 2 S homeolog antikoerper, paired like homeodomain 2 L homeolog antikoerper, PITX2 antikoerper, Pitx2 antikoerper, pitx2 antikoerper, pitx2.S antikoerper, pitx2.L antikoerper

Hintergrund: This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.,PITX2,ARP1,ASGD4,Brx1,IDG2,IGDS,IGDS2,IHG2,IRID2,Otlx2,PTX2,RGS,RIEG,RIEG1,RS,Epigenetics & Nuclear Signaling,Transcription Factors,Cell Biology & Developmental Biology,Cardiovascular,Heart,Cardiogenesis,PITX2

Molekulargewicht: 30 kDa/35 kDa

Gen-ID: 5308

UniProt: Q99697

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development