Lamin B1 Antikörper (AA 397-586)

Produktnummer ABIN3015698

Produktdetails anti-Lamin B1 Antikörper

Target: Lamin B1 (LMNB1)

Bindungsspezifität: AA 397-586

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lamin B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequenz: RVTVSRASSS RSVRTTRGKR KRVDVEESEA SSSVSISHSA SATGNVCIEE IDVDGKFIRL KNTSEQDQPM GGWEMIRKIG DTSVSYKYTS RYVLKAGQTV TIWAANAGVT ASPPTDLIWK NQNSWGTGED VKVILKNSQG EEVAQRSTVF KTTIPEEEEE EEEAAGVVVE EELFHQQGTP RASNRSCAIM

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 397-586 of human Lamin B1 (NP_005564.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-Lamin B1 Antikörper (ABIN3015698)

Cheng, Wei, Xie, Peng, Yan, Qin, Liu, Xu, Li, Zhang: "Alleviation of Toxicity Caused by Overactivation of Pparα through Pparα-Inducible miR-181a2." in: Molecular therapy. Nucleic acids, Vol. 9, pp. 195-206, (2017) (PubMed).

Ma, Fang, Luo, Yang, Wang, Zhang, Wang, Chen, Chan, Liu: "The C-ETS2-TFEB Axis Promotes Neuron Survival under Oxidative Stress by Regulating Lysosome Activity." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 4693703, (2017) (PubMed).

Details zu Lamin B1

Target: Lamin B1 (LMNB1)

Andere Bezeichnung: LMNB1 (LMNB1 Produkte)

Synonyme: MGC52550 antikoerper, Lamin-L(I) antikoerper, lamin-b antikoerper, lmn antikoerper, lmn2 antikoerper, lmnb antikoerper, LMNB1 antikoerper, ADLD antikoerper, LMN antikoerper, LMN2 antikoerper, LMNB antikoerper, fc06g01 antikoerper, wu:fc06g01 antikoerper, lamin B1 L homeolog antikoerper, lamin B1 antikoerper, lmnb1.L antikoerper, lmnb1 antikoerper, LMNB1 antikoerper, Lmnb1 antikoerper

Hintergrund: This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.,ADLD,LMN,LMN2,LMNB,Lamin B1,LMNB1,lamin-B1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Intermediate Filaments,LMNB1

Molekulargewicht: 66 kDa

Gen-ID: 4001

UniProt: P20700

Pathways: Apoptose, Caspase Kaskade in der Apoptose