ANGPTL4 Antikörper (AA 26-406)

Produktnummer ABIN3015827

Produktdetails anti-ANGPTL4 Antikörper

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Bindungsspezifität: AA 26-406

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANGPTL4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: GPVQSKSPRF ASWDEMNVLA HGLLQLGQGL REHAERTRSQ LSALERRLSA CGSACQGTEG STDLPLAPES RVDPEVLHSL QTQLKAQNSR IQQLFHKVAQ QQRHLEKQHL RIQHLQSQFG LLDHKHLDHE VAKPARRKRL PEMAQPVDPA HNVSRLHRLP RDCQELFQVG ERQSGLFEIQ PQGSPPFLVN CKMTSDGGWT VIQRRHDGSV DFNRPWEAYK AGFGDPHGEF WLGLEKVHSI TGDRNSRLAV QLRDWDGNAE LLQFSVHLGG EDTAYSLQLT APVAGQLGAT TVPPSGLSVP FSTWDQDHDL RRDKNCAKSL SGGWWFGTCS HSNLNGQYFR SIPQQRQKLK KGIFWKTWRG RYYPLQATTM LIQPMAAEAA S

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 26-406 of human ANGPTL4 (NP_647475.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ANGPTL4

Target: ANGPTL4 (Angiopoietin-Like 4 (ANGPTL4))

Andere Bezeichnung: ANGPTL4 (ANGPTL4 Produkte)

Synonyme: ANGPTL2 antikoerper, ARP4 antikoerper, FIAF antikoerper, HFARP antikoerper, NL2 antikoerper, PGAR antikoerper, pp1158 antikoerper, Arp4 antikoerper, Bk89 antikoerper, Fiaf antikoerper, Hfarp antikoerper, Ng27 antikoerper, Pgar antikoerper, Pgarg antikoerper, Pp1158 antikoerper, ANGPTL4 antikoerper, fiaf antikoerper, im:7144703 antikoerper, si:rp71-39b20.7 antikoerper, angiopoietin like 4 antikoerper, angiopoietin-like 4 antikoerper, ANGPTL4 antikoerper, Angptl4 antikoerper, angptl4 antikoerper

Hintergrund: This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.,ANGPTL4,ARP4,FIAF,HARP,HFARP,NL2,PGAR,TGQTL,UNQ171,pp1158,Cancer,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Cardiovascular,Angiogenesis,Hypoxia,Hypoxia-Regulated,Lipids,ANGPTL4

Molekulargewicht: 26 kDa/40 kDa/45 kDa

Gen-ID: 51129

UniProt: Q9BY76

Pathways: Regulation of Lipid Metabolism by PPARalpha