Chitotriosidase 1 Antikörper (AA 217-466)

Produktnummer ABIN3015833

Produktdetails anti-Chitotriosidase 1 Antikörper

Target: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Bindungsspezifität: AA 217-466

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Chitotriosidase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SWEKVTGHNS PLYKRQEESG AAASLNVDAA VQQWLQKGTP ASKLILGMPT YGRSFTLASS SDTRVGAPAT GSGTPGPFTK EGGMLAYYEV CSWKGATKQR IQDQKVPYIF RDNQWVGFDD VESFKTKVSY LKQKGLGGAM VWALDLDDFA GFSCNQGRYP LIQTLRQELS LPYLPSGTPE LEVPKPGQPS EPEHGPSPGQ DTFCQGKADG LYPNPRERSS FYSCAAGRLF QQSCPTGLVF SNSCKCCTWN

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 217-466 of human CHIT1 (NP_003456.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Chitotriosidase 1

Target: Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))

Andere Bezeichnung: CHIT1 (CHIT1 Produkte)

Synonyme: CHI3 antikoerper, CHIT antikoerper, CHITD antikoerper, CHIT1 antikoerper, chio antikoerper, 2300002L19Rik antikoerper, chitinase 1 antikoerper, chitinase 1 (chitotriosidase) antikoerper, CHIT1 antikoerper, chit1 antikoerper, Chit1 antikoerper

Hintergrund: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.,CHIT1,CHI3,CHIT,CHITD,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CHIT1

Molekulargewicht: 43 kDa/48 kDa/49 kDa/51 kDa

Gen-ID: 1118

UniProt: Q13231