EIF5A Antikörper (AA 1-154)

Produktnummer ABIN3015836

Produktdetails anti-EIF5A Antikörper

Target: EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))

Bindungsspezifität: AA 1-154

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF5A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MADDLDFETG DAGASATFPM QCSALRKNGF VVLKGRPCKI VEMSTSKTGK HGHAKVHLVG IDIFTGKKYE DICPSTHNMD VPNIKRNDFQ LIGIQDGYLS LLQDSGEVRE DLRLPEGDLG KEIEQKYDCG EEILITVLSA MTEEAAVAIK AMAK

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human eIF5A (NP_001137234.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EIF5A

Target: EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))

Andere Bezeichnung: EIF5A (EIF5A Produkte)

Synonyme: EIF-5A antikoerper, EIF5A1 antikoerper, eIF5AI antikoerper, EIF5A antikoerper, zgc:55504 antikoerper, zgc:77429 antikoerper, wu:fb05b06 antikoerper, wu:fc23f04 antikoerper, wu:fc61c10 antikoerper, AA410058 antikoerper, D19Wsu54e antikoerper, Eif4d antikoerper, Eif5a1 antikoerper, eIF-4D antikoerper, eIF-5A antikoerper, eIF-5A-1 antikoerper, eIF-5A1 antikoerper, zgc:77099 antikoerper, wu:fb17e01 antikoerper, wu:fb63h04 antikoerper, wu:fk81e04 antikoerper, DDBDRAFT_0191442 antikoerper, DDBDRAFT_0218663 antikoerper, DDB_0191442 antikoerper, DDB_0218663 antikoerper, 1296 antikoerper, CG3186 antikoerper, Dmel\\CG3186 antikoerper, anon-EST:fe2H10 antikoerper, eIF5A antikoerper, eIF5a antikoerper, l(2)01296 antikoerper, EIF-5A1 antikoerper, NeIF-5A3 antikoerper, eif5a antikoerper, iff-2 antikoerper, eukaryotic translation initiation factor 5A antikoerper, eukaryotic translation initiation factor 5A2 antikoerper, eukaryotic translation initiation factor 5a antikoerper, putative eukaryotic initiation factor 5a antikoerper, CG3186 gene product from transcript CG3186-RB antikoerper, eukaryotic translation initiation factor 5A-1 antikoerper, eukaryotic translation initiation factor 5A L homeolog antikoerper, EIF5A antikoerper, eif5a2 antikoerper, Eif5a antikoerper, eif5a antikoerper, tif5A antikoerper, Tb11.03.0410 antikoerper, LOC5579111 antikoerper, EIF5A1 antikoerper, eIF-5A antikoerper, LOC107820748 antikoerper, eif5a.L antikoerper

Hintergrund: MRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1 Rex protein and of human immunodeficiency virus type 1 (HIV-1 Rev protein, essential for mRNA export of retroviral transcripts.,EIF5A,EIF-5A,EIF5A1,eIF5AI,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF2,Cell Biology & Developmental Biology,Apoptosis,EIF5A

Molekulargewicht: 16 kDa/20 kDa

Gen-ID: 1984

UniProt: P63241

Pathways: Regulation of Muscle Cell Differentiation