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Produktnummer ABIN3015855
  • Target Alle KPNA4 Antikörper anzeigen
    KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 1-240
    Reaktivität
    • 42
    • 35
    • 15
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Human
    Wirt
    • 49
    • 1
    • 1
    Kaninchen
    Klonalität
    • 50
    • 1
    Polyklonal
    Konjugat
    • 21
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KPNA4 Antikörper ist unkonjugiert
    Applikation
    • 38
    • 20
    • 14
    • 13
    • 9
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequenz
    MADNEKLDNQ RLKNFKNKGR DLETMRRQRN EVVVELRKNK RDEHLLKRRN VPHEDICEDS DIDGDYRVQN TSLEAIVQNA SSDNQGIQLS AVQAARKLLS SDRNPPIDDL IKSGILPILV HCLERDDNPS LQFEAAWALT NIASGTSEQT QAVVQSNAVP LFLRLLHSPH QNVCEQAVWA LGNIIGDGPQ CRDYVISLGV VKPLLSFISP SIPITFLRNV TWVMVNLCRH KDPPPPMETI
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human KPNA4 (NP_002259.1).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Li, Lu, Huang, Lv: "Porcine circovirus type 2 inhibits inter-β expression by targeting Karyopherin alpha-3 in PK-15 cells." in: Virology, Vol. 520, pp. 75-82, (2018) (PubMed).

  • Target
    KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
    Andere Bezeichnung
    KPNA4 (KPNA4 Produkte)
    Hintergrund
    The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.,KPNA4,IPOA3,QIP1,SRP3,Signal Transduction,KPNA4
    Molekulargewicht
    57 kDa
    Gen-ID
    3840
    UniProt
    O00629
    Pathways
    Protein targeting to Nucleus
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