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Histone 3 Antikörper (H3K9me3)

H3 Reaktivität: Human WB, IHC, IF, ChIP, DB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3016030
  • Target Alle Histone 3 (H3) Antikörper anzeigen
    Histone 3 (H3)
    Bindungsspezifität
    • 56
    • 49
    • 47
    • 43
    • 42
    • 36
    • 35
    • 34
    • 34
    • 33
    • 33
    • 32
    • 31
    • 30
    • 27
    • 27
    • 23
    • 23
    • 22
    • 22
    • 21
    • 18
    • 17
    • 17
    • 16
    • 16
    • 16
    • 16
    • 15
    • 15
    • 15
    • 14
    • 13
    • 13
    • 13
    • 13
    • 12
    • 12
    • 12
    • 11
    • 11
    • 10
    • 10
    • 10
    • 9
    • 9
    • 8
    • 8
    • 8
    • 8
    H3K9me3
    Reaktivität
    • 1320
    • 914
    • 841
    • 58
    • 41
    • 41
    • 40
    • 40
    • 39
    • 35
    • 34
    • 31
    • 26
    • 22
    • 19
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 1136
    • 238
    • 12
    • 5
    Kaninchen
    Klonalität
    • 1059
    • 331
    • 1
    Polyklonal
    Konjugat
    • 779
    • 72
    • 47
    • 46
    • 44
    • 44
    • 44
    • 44
    • 29
    • 27
    • 18
    • 18
    • 18
    • 17
    • 17
    • 17
    • 17
    • 17
    • 17
    • 17
    • 17
    • 17
    • 7
    • 1
    Dieser Histone 3 Antikörper ist unkonjugiert
    Applikation
    • 991
    • 368
    • 364
    • 298
    • 238
    • 188
    • 173
    • 163
    • 163
    • 153
    • 139
    • 128
    • 112
    • 48
    • 35
    • 34
    • 32
    • 22
    • 16
    • 14
    • 7
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Dot Blot (DB)
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Methylated Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    A synthetic methylated peptide corresponding to residues surrounding K9 of human histone H3
    Isotyp
    IgG
    Top Product
    Discover our top product H3 Primärantikörper
  • Applikationshinweise
    DB,1:500 - 1:2000,WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,ChIP,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Zuo, Rong, Li, Lv, Lan, Tong: "The histone methyltransferase SETD2 is required for expression of acrosin-binding protein 1 and protamines and essential for spermiogenesis in mice." in: The Journal of biological chemistry, Vol. 293, Issue 24, pp. 9188-9197, (2019) (PubMed).

    Zhao, Zhang, Chen, Wang, Li, Cheng, Duan, Zhu, Wei, Li, Wu, Han, Yu, Gao, Li, Wong: "Dissecting the precise role of H3K9 methylation in crosstalk with DNA maintenance methylation in mammals." in: Nature communications, Vol. 7, pp. 12464, (2018) (PubMed).

    Fan, Lv, Huo, Wu, Wang, Cheng, Liu, Tang, Zhang, Zhang, Zheng, Wu, Wen: "The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes." in: Genome research, Vol. 28, Issue 2, pp. 192-202, (2018) (PubMed).

    Yu, Liu, Liu, Wang, Liu, Miao, Du, Yang: "Ascorbic acid induces global epigenetic reprogramming to promote meiotic maturation and developmental competence of porcine oocytes." in: Scientific reports, Vol. 8, Issue 1, pp. 6132, (2018) (PubMed).

    Cao, Liu, Yue, Liu, Pei, Gu, Wang, Jia: "Iron chelation inhibits cancer cell growth and modulates global histone methylation status in colorectal cancer." in: Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, Vol. 31, Issue 5, pp. 797-805, (2018) (PubMed).

    Yin, Jiang, Jiang, Gao, Wang, Fan, Khan, Jabeen, Khan, Ali, Xu, Pandita, Fan, Zhang, Shi: "Histone acetyltransferase KAT8 is essential for mouse oocyte development by regulating reactive oxygen species levels." in: Development (Cambridge, England), Vol. 144, Issue 12, pp. 2165-2174, (2017) (PubMed).

    Zhao, Lei, Zhang, Zheng, Wang, Zhao, Li, Ye, Li, Wei, Wu: "Global histone modification profiling reveals the epigenomic dynamics during malignant transformation in a four-stage breast cancer model." in: Clinical epigenetics, Vol. 8, pp. 34, (2016) (PubMed).

  • Target
    Histone 3 (H3)
    Andere Bezeichnung
    Histone H3 (H3 Produkte)
    Hintergrund
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.,H3.4,H3/g,H3FT,H3t,HIST3H3,Histone H3,HIST1H3A,Signal Transduction,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Epigenetics & Nuclear Signaling,Epigenetic Modifications,Methylation,Histone H3
    Molekulargewicht
    15 kDa
    Gen-ID
    8290
    UniProt
    Q16695
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