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Mps1 Antikörper (AA 517-856)

TTK Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3016144
  • Target Alle Mps1 (TTK) Antikörper anzeigen
    Mps1 (TTK)
    Bindungsspezifität
    • 15
    • 15
    • 10
    • 8
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 517-856
    Reaktivität
    • 80
    • 17
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 71
    • 10
    • 1
    Kaninchen
    Klonalität
    • 73
    • 9
    Polyklonal
    Konjugat
    • 37
    • 7
    • 7
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Mps1 Antikörper ist unkonjugiert
    Applikation
    • 62
    • 46
    • 26
    • 13
    • 13
    • 9
    • 8
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    ISVKGRIYSI LKQIGSGGSS KVFQVLNEKK QIYAIKYVNL EEADNQTLDS YRNEIAYLNK LQQHSDKIIR LYDYEITDQY IYMVMECGNI DLNSWLKKKK SIDPWERKSY WKNMLEAVHT IHQHGIVHSD LKPANFLIVD GMLKLIDFGI ANQMQPDTTS VVKDSQVGTV NYMPPEAIKD MSSSRENGKS KSKISPKSDV WSLGCILYYM TYGKTPFQQI INQISKLHAI IDPNHEIEFP DIPEKDLQDV LKCCLKRDPK QRISIPELLA HPYVQIQTHP VNQMAKGTTE EMKYVLGQLV GLNSPNSILK AAKTLYEHYS GGESHNSSSS KTFEKKRGKK
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 517-856 of human TTK (NP_001160163.1).
    Isotyp
    IgG
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  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    Mps1 (TTK)
    Andere Bezeichnung
    TTK (TTK Produkte)
    Synonyme
    CT96 antikoerper, ESK antikoerper, MPH1 antikoerper, MPS1 antikoerper, MPS1L1 antikoerper, PYT antikoerper, AL022661 antikoerper, Esk1 antikoerper, Mps1 antikoerper, esk antikoerper, mps1 antikoerper, ncp antikoerper, Ttk protein kinase antikoerper, TTK protein kinase antikoerper, ttk protein kinase antikoerper, Ttk antikoerper, TTK antikoerper, ttk antikoerper
    Hintergrund
    This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants.,TTK,CT96,ESK,MPH1,MPS1,MPS1L1,PYT,Epigenetics & Nuclear Signaling,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Centromere,TTK
    Molekulargewicht
    96 kDa/97 kDa
    Gen-ID
    7272
    UniProt
    P33981
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