PRG2 Antikörper (AA 17-222)

Produktnummer ABIN3016204

Produktdetails anti-PRG2 Antikörper

Target: PRG2 (Bone Marrow Proteoglycan (PRG2))

Bindungsspezifität: AA 17-222

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: LHLRSETSTF ETPLGAKTLP EDEETPEQEM EETPCRELEE EEEWGSGSED ASKKDGAVES ISVPDMVDKN LTCPEEEDTV KVVGIPGCQT CRYLLVRSLQ TFSQAWFTCR RCYRGNLVSI HNFNINYRIQ CSVSALNQGQ VWIGGRITGS GRCRRFQWVD GSRWNFAYWA AHQPWSRGGH CVALCTRGGH WRRAHCLRRL PFICSY

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 17-222 of human PRG2 (NP_002719.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PRG2

Target: PRG2 (Bone Marrow Proteoglycan (PRG2))

Andere Bezeichnung: PRG2 (PRG2 Produkte)

Synonyme: MBP antikoerper, mMBP antikoerper, mMBP-1 antikoerper, BMPG antikoerper, MBP1 antikoerper, proteoglycan 2, bone marrow antikoerper, proteoglycan 2 antikoerper, proteoglycan 2, pro eosinophil major basic protein antikoerper, Prg2 antikoerper, PRG2 antikoerper

Hintergrund: The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,PRG2,BMPG,MBP,MBP1,proMBP,PRG2

Molekulargewicht: 23 kDa/25 kDa

Gen-ID: 5553

UniProt: P13727