Metabotropic Glutamate Receptor 3 Antikörper (AA 23-170)

Produktnummer ABIN3016218

Produktdetails anti-Metabotropic Glutamate Receptor 3 Antikörper

Target: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Bindungsspezifität: AA 23-170

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Metabotropic Glutamate Receptor 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LGDHNFLRRE IKIEGDLVLG GLFPINEKGT GTEECGRINE DRGIQRLEAM LFAIDEINKD DYLLPGVKLG VHILDTCSRD TYALEQSLEF VRASLTKVDE AEYMCPDGSY AIQENIPLLI AGVIGGSYSS VSIQVANLLR LFQIPQIS

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 23-170 of human GRM3 (NP_000831.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Metabotropic Glutamate Receptor 3

Target: Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))

Andere Bezeichnung: GRM3 (GRM3 Produkte)

Synonyme: GLUR3 antikoerper, GPRC1C antikoerper, MGLUR3 antikoerper, mGlu3 antikoerper, 0710001G23Rik antikoerper, Gprc1c antikoerper, mGluR3 antikoerper, glutamate metabotropic receptor 3 antikoerper, glutamate receptor, metabotropic 3 antikoerper, GRM3 antikoerper, Grm3 antikoerper

Hintergrund: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.,GRM3,GLUR3,GPRC1C,MGLUR3,mGlu3,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,GRM3

Molekulargewicht: 60 kDa/98 kDa

Gen-ID: 2913

UniProt: Q14832

Pathways: cAMP Metabolic Process, Synaptic Membrane