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Metabotropic Glutamate Receptor 3 Antikörper (AA 23-170)
GRM3
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN6219629
Produktdetails anti-Metabotropic Glutamate Receptor 3 Antikörper
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Target
Alle Metabotropic Glutamate Receptor 3 (GRM3) Antikörper anzeigen
Metabotropic Glutamate Receptor 3 (GRM3)
(Glutamate Receptor, Metabotropic 3 (GRM3))
Bindungsspezifität
Alle Epitope für Metabotropic Glutamate Receptor 3 Antikörper
AA 23-170
Reaktivität
Alle Reaktivitäten für Metabotropic Glutamate Receptor 3 Antikörper
Human
Wirt
Alle Wirte für Metabotropic Glutamate Receptor 3 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für Metabotropic Glutamate Receptor 3 Antikörper
Polyklonal
Konjugat
Alle Konjugate für Metabotropic Glutamate Receptor 3 Antikörper
Dieser Metabotropic Glutamate Receptor 3 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Metabotropic Glutamate Receptor 3 Antikörper
Western Blotting (WB)
Sequenz
LGDHNFLRRE IKIEGDLVLG GLFPINEKGT GTEECGRINE DRGIQRLEAM LFAIDEINKD DYLLPGVKLG VHILDTCSRD TYALEQSLEF VRASLTKVDE AEYMCPDGSY AIQENIPLLI AGVIGGSYSS VSIQVANLLR LFQIPQIS
Kreuzreaktivität
Human, Maus
Produktmerkmale
Polyclonal Antibodies
Aufreinigung
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 23-170 of human GRM3 (NP_000831.2).
Isotyp
IgG
Top Product
Discover our top product GRM3 Primärantikörper
Alternativen
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anti-Glutamate Receptor, Metabotropic 3 (GRM3) (N-Term) antibody
GRM3
Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Affe, Hamster, Schwein
IHC, ICC, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
WB,1:500 - 1:2000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Details zu Metabotropic Glutamate Receptor 3
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Target
Metabotropic Glutamate Receptor 3 (GRM3)
(Glutamate Receptor, Metabotropic 3 (GRM3))
Andere Bezeichnung
GRM3 (GRM3 Produkte )
Synonyme
GLUR3 antikoerper, GPRC1C antikoerper, MGLUR3 antikoerper, mGlu3 antikoerper, 0710001G23Rik antikoerper, Gprc1c antikoerper, mGluR3 antikoerper, glutamate metabotropic receptor 3 antikoerper, glutamate receptor, metabotropic 3 antikoerper, GRM3 antikoerper, Grm3 antikoerper
Hintergrund
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.,GRM3,GLUR3,GPRC1C,MGLUR3,mGlu3,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,GRM3
Molekulargewicht
60 kDa/98 kDa
Gen-ID
2913
UniProt
Q14832
Pathways
cAMP Metabolic Process , Synaptic Membrane
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