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CCR2 Antikörper (AA 315-374)

CCR2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3016845
  • Target Alle CCR2 Antikörper anzeigen
    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
    Bindungsspezifität
    • 16
    • 9
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 315-374
    Reaktivität
    • 97
    • 47
    • 40
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 82
    • 14
    • 4
    • 1
    Kaninchen
    Klonalität
    • 77
    • 23
    • 1
    Polyklonal
    Konjugat
    • 41
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CCR2 Antikörper ist unkonjugiert
    Applikation
    • 41
    • 26
    • 25
    • 15
    • 13
    • 12
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    LFHIALGCRI APLQKPVCGG PGVRPGKNVK VTTQGLLDGR GKGKSIGRAP EASLQDKEGA
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 315-374 of human CCR2 (NP_001116513.2).
    Isotyp
    IgG
    Top Product
    Discover our top product CCR2 Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Deci, Ferguson, Scatigno, Nguyen: "Modulating Macrophage Polarization through CCR2 Inhibition and Multivalent Engagement." in: Molecular pharmaceutics, Vol. 15, Issue 7, pp. 2721-2731, (2018) (PubMed).

  • Target
    CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
    Andere Bezeichnung
    CCR2 (CCR2 Produkte)
    Synonyme
    CC-CKR-2 antikoerper, CCR-2 antikoerper, CCR2A antikoerper, CCR2B antikoerper, CD192 antikoerper, CKR2 antikoerper, CKR2A antikoerper, CKR2B antikoerper, CMKBR2 antikoerper, MCP-1-R antikoerper, ACKR5 antikoerper, CKRX antikoerper, CRAM antikoerper, CRAM-A antikoerper, CRAM-B antikoerper, HCR antikoerper, Cc-ckr-2 antikoerper, Ccr2a antikoerper, Ccr2b antikoerper, Ckr2 antikoerper, Ckr2a antikoerper, Ckr2b antikoerper, Cmkbr2 antikoerper, mJe-r antikoerper, C-C motif chemokine receptor 2 antikoerper, C-C motif chemokine receptor like 2 antikoerper, chemokine (C-C motif) receptor 2 antikoerper, CCR2 antikoerper, CCRL2 antikoerper, Ccr2 antikoerper, LOC484790 antikoerper
    Hintergrund
    This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.,CCR2,CC-CKR-2,CCR-2,CCR2A,CCR2B,CD192,CKR2,CKR2A,CKR2B,CMKBR2,MCP-1-R,FLJ78302,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,Chemokines,Chemokine,Cardiovascular,CCR2
    Molekulargewicht
    41 kDa
    Gen-ID
    729230
    UniProt
    P41597
    Pathways
    cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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