DUSP1 Antikörper

Produktnummer ABIN3016981

Produktdetails anti-DUSP1 Antikörper

Target: DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide of human DUSP1 / MKP1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DUSP1

Target: DUSP1 (Dual Specificity Phosphatase 1 (DUSP1))

Andere Bezeichnung: DUSP1 (DUSP1 Produkte)

Synonyme: CL100 antikoerper, HVH1 antikoerper, MKP-1 antikoerper, MKP1 antikoerper, PTPN10 antikoerper, 3CH134 antikoerper, Mkp1 antikoerper, Ptpn16 antikoerper, DUSP1 antikoerper, U19515 antikoerper, erp antikoerper, mkp-1 antikoerper, cb269 antikoerper, sb:cb269 antikoerper, zgc:55920 antikoerper, id:ibd2586 antikoerper, wu:fd19g02 antikoerper, wu:fe50g09 antikoerper, XCL100 antikoerper, dual specificity phosphatase 1 antikoerper, dual specificity phosphatase 1 S homeolog antikoerper, DUSP1 antikoerper, Dusp1 antikoerper, dusp1 antikoerper, dusp1.S antikoerper

Hintergrund: The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.,DUSP1,CL100,HVH1,MKP-1,MKP1,PTPN10,Signal Transduction,Kinase,MAPK-Erk Signaling Pathway,MAPK-JNK Signaling Pathway,DUSP1

Molekulargewicht: 39 kDa

Gen-ID: 1843

UniProt: P28562