GRPR Antikörper (AA 235-384)
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- Target Alle GRPR Antikörper anzeigen
- GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
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Bindungsspezifität
- AA 235-384
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GRPR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- KNLIQSAYNL PVEGNIHVKK QIESRKRLAK TVLVFVGLFA FCWLPNHVIY LYRSYHYSEV DTSMLHFVTS ICARLLAFTN SCVNPFALYL LSKSFRKQFN TQLLCCQPGL IIRSHSTGRS TTCMTSLKST NPSVATFSLI NGNICHERYV
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 235-384 of human GRPR (NP_005305.1).
- Isotyp
- IgG
- Top Product
- Discover our top product GRPR Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- GRPR (Gastrin-Releasing Peptide Receptor (GRPR))
- Andere Bezeichnung
- GRPR (GRPR Produkte)
- Hintergrund
- Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.,GRPR,BB2,BB2R,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,GRPR
- Molekulargewicht
- 43 kDa
- Gen-ID
- 2925
- UniProt
- P30550
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