RAD50 Antikörper (AA 1-100)
(1 reference)-
- Target Alle RAD50 Antikörper anzeigen
- RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
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Bindungsspezifität
- AA 1-100
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RAD50 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
- Sequenz
- MSRIEKMSIL GVRSFGIEDK DKQIITFFSP LTILVGPNGA GKTTIIECLK YICTGDFPPG TKGNTFVHDP KVAQETDVRA QIRLQFRDVN GELIAVQRSM
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Rad50 (NP_005723.2).
- Isotyp
- IgG
- Top Product
- Discover our top product RAD50 Primärantikörper
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anti-RAD50 Homolog (S. Cerevisiae) (RAD50) antibody
RAD50 Reaktivität: Human, Maus, Ratte WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 228-359) antibodyRAD50 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 3D2G10 unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 672-786) antibodyRAD50 Reaktivität: Human WB, IF Wirt: Maus Monoclonal 13-RAD50 unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 228-359) antibodyRAD50 Reaktivität: Human ELISA Wirt: Maus Monoclonal 5A8E5 unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (Internal Region) antibodyRAD50 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 1-234) antibodyRAD50 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) antibodyRAD50 Reaktivität: Human WB Wirt: Kaninchen Monoclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 817-872) antibodyRAD50 Reaktivität: Human, Maus WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 911-938), (C-Term) antibodyRAD50 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB40014 unconjugated
anti-RAD50 Homolog (S. Cerevisiae) (RAD50) (AA 700-750) antibodyRAD50 Reaktivität: Human, Maus, Rind (Kuh), Kaninchen, Hund IHC, IF, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:20 - 1:50
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).
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: "The transcription factor GATA3 is required for homologous recombination repair by regulating CtIP expression." in: Oncogene, Vol. 36, Issue 36, pp. 5168-5176, (2017) (PubMed).
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- Target
- RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))
- Andere Bezeichnung
- RAD50 (RAD50 Produkte)
- Hintergrund
- The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.,RAD50,NBSLD,RAD502,hRad50,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Cell Cycle,G2/M DNA Damage Checkpoint,RAD50
- Molekulargewicht
- 138 kDa/153 kDa/154 kDa
- Gen-ID
- 10111
- UniProt
- Q92878
- Pathways
- DNA Reparatur, Protein targeting to Nucleus
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