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Cofilin Antikörper (pSer3)
CFL1
Reaktivität: Human
WB, IHC, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN1681472
Produktdetails anti-Cofilin Antikörper
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Target
Alle Cofilin (CFL1) Antikörper anzeigen
Cofilin (CFL1)
(Cofilin 1 (CFL1))
Bindungsspezifität
Alle Epitope für Cofilin Antikörper
pSer3
Reaktivität
Alle Reaktivitäten für Cofilin Antikörper
Human
Wirt
Alle Wirte für Cofilin Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für Cofilin Antikörper
Polyklonal
Konjugat
Alle Konjugate für Cofilin Antikörper
Dieser Cofilin Antikörper ist unkonjugiert
Applikation
Alle Applikationen für Cofilin Antikörper
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Kreuzreaktivität
Human, Maus, Ratte
Produktmerkmale
Phosphorylated Antibodies
Aufreinigung
Affinity purification
Immunogen
A phospho specific peptide corresponding to residues surrounding S3 of human CFL1
Isotyp
IgG
Top Product
Discover our top product CFL1 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:100 - 1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Referenzen für anti-Cofilin Antikörper (ABIN1681472)
(ausblenden)
Hu, Guo, Feng, Zhang, Zhou, Ma, Shen, Tong, Yan, Zhu, Bian, Lai, Deng, Ding : "MIF, secreted by human hepatic sinusoidal endothelial cells, promotes chemotaxis and outgrowth of colorectal cancer in liver prometastasis. " in: Oncotarget , Vol. 6 , Issue 26 , pp. 22410-23 , (2016 ) (PubMed ).
Details zu Cofilin
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Target
Cofilin (CFL1)
(Cofilin 1 (CFL1))
Andere Bezeichnung
CFL1 (CFL1 Produkte )
Synonyme
cfl1 antikoerper, xac1 antikoerper, xac2 antikoerper, cfl antikoerper, cb86 antikoerper, sb:cb86 antikoerper, zgc:56501 antikoerper, wu:fb18a04 antikoerper, wu:fk77b03 antikoerper, 12/8 antikoerper, ADF antikoerper, ADF/cofilin antikoerper, Adf antikoerper, CG4254 antikoerper, Cadf antikoerper, D-cof antikoerper, D61 antikoerper, Dmel\\CG4254 antikoerper, T8 antikoerper, Tsr antikoerper, cofilin antikoerper, cofilin/ADF antikoerper, cofilin/actin depolymerizing factor homolog antikoerper, l(2)03101 antikoerper, l(2)k03101 antikoerper, l(2)k05633 antikoerper, l(2)k13409 antikoerper, ntf antikoerper, CFL antikoerper, AA959946 antikoerper, Cof antikoerper, CFL1 antikoerper, cofilin 1 (non-muscle) L homeolog antikoerper, cofilin 1 (non-muscle) antikoerper, cofilin 1 (non-muscle), like antikoerper, cofilin 1 antikoerper, twinstar antikoerper, cofilin antikoerper, cofilin 1, non-muscle antikoerper, Contrafreeloading antikoerper, cfl1.L antikoerper, cfl1 antikoerper, cfl1l antikoerper, CFL1 antikoerper, tsr antikoerper, COF1 antikoerper, TSTA_042790 antikoerper, Cfl1 antikoerper, CFL antikoerper
Hintergrund
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH -dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004],CFL1,CFL,HEL-S-15,cofilin,cofilin-1,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Adhesion,Cytoskeleton,Microfilaments,Microtubules,Actins,TGF-b-Smad Signaling Pathway,Immunology & Inflammation,Neuroscience,Cell Type Marker,Cardiovascular,Heart,Contractility,Neuron marker,Axon marker,Protein phosphorylation,CFL1
Molekulargewicht
18 kDa
Gen-ID
1072
UniProt
P23528
Pathways
Regulation of Cell Size , Tube Formation , Protein targeting to Nucleus , CXCR4-mediated Signaling Events
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