MYL12A Antikörper (pSer18)

Produktnummer ABIN3020385

Produktdetails anti-MYL12A Antikörper

Target: MYL12A (Myosin, Light Chain 12A, Regulatory, Non-Sarcomeric (MYL12A))

Bindungsspezifität: pSer18

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYL12A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität: Human, Ratte

Produktmerkmale: Phosphorylated Antibodies

Immunogen: A phospho specific peptide corresponding to residues surrounding S18 of human MYL12A

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-MYL12A Antikörper (ABIN3020385)

Niu, Pi, Baral, Xia, He, Li, Jin, Li, Wang, Mao, Hu: "P2Y12 Promotes Migration of Vascular Smooth Muscle Cells Through Cofilin Dephosphorylation During Atherogenesis." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 37, Issue 3, pp. 515-524, (2017) (PubMed).

Details zu MYL12A

Target: MYL12A (Myosin, Light Chain 12A, Regulatory, Non-Sarcomeric (MYL12A))

Andere Bezeichnung: MYL12A (MYL12A Produkte)

Synonyme: MLCB antikoerper, MRCL3 antikoerper, MRLC3 antikoerper, MYL2B antikoerper, RGD1309537 antikoerper, Rlc-a antikoerper, myosin light chain 12A antikoerper, MYL12A antikoerper, Myl12a antikoerper

Hintergrund: This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.,MYL12A,HEL-S-24,MLC-2B,MLCB,MRCL3,MRLC3,MYL2B,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Motor Proteins,Actins,Protein phosphorylation,MYL12A

Molekulargewicht: 19 kDa

Gen-ID: 10627

UniProt: P19105