GAPDH Antikörper

Produktnummer ABIN3020541

Produktdetails anti-GAPDH Antikörper

Target: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GAPDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Loading control Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human GAPDH

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:5000 - 1:20000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-GAPDH Antikörper (ABIN3020541)

Wu, Xiong, Li, Yang, Ge et al.: "Integrated Proteomic and Transcriptomic Analysis Reveals Long Noncoding RNA HOX Transcript Antisense Intergenic RNA (HOTAIR) Promotes Hepatocellular Carcinoma Cell Proliferation by Regulating Opioid ..." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 146-159, (2019) (PubMed).

Han, Cai, Gao, Meng, Gao, Wu, Duan, Wang, Dinislam, Lin, Kang, Jiang: "Loss of ATRX suppresses ATM dependent DNA damage repair by modulating H3K9me3 to enhance temozolomide sensitivity in glioma." in: Cancer letters, Vol. 419, pp. 280-290, (2019) (PubMed).

Zhang, Qian, Zheng, Qian, Wang, Thu, Zhang, Zhou, Tu, Liu, Li, Yang, Li, Xu: "Jujuboside A promotes Aβ clearance and ameliorates cognitive deficiency in Alzheimer's disease through activating Axl/HSP90/PPARγ pathway." in: Theranostics, Vol. 8, Issue 15, pp. 4262-4278, (2018) (PubMed).

Yu, Chen, Li, Yang, Zhang, Huangfu, Zheng, Zhao, Lv, Hong, Liang, Shan: "YAP1 contributes to NSCLC invasion and migration by promoting Slug transcription via the transcription co-factor TEAD." in: Cell death & disease, Vol. 9, Issue 5, pp. 464, (2018) (PubMed).

Peng, Wang, Shu, Yang, Wang, Ouyang, Shen, Hou, Zhao, Wang, Zhang, Liu, Zhao: "Raddeanin a Suppresses Glioblastoma Growth by Inducing ROS Generation and Subsequent JNK Activation to Promote Cell Apoptosis." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 47, Issue 3, pp. 1108-1121, (2018) (PubMed).

Nie, Huang, Deng, Bao, Liu, Feng, Wang, Chen, Qi, Pan: "The purine receptor P2X7R regulates the release of pro-inflammatory cytokines in human craniopharyngioma." in: Endocrine-related cancer, Vol. 24, Issue 6, pp. 287-296, (2018) (PubMed).

Wan, Ashraf, Ye, Duan, Zohaib, Wang, Chen, Zhu, Li, Chen, Cao: "MicroRNA-22 negatively regulates poly(I:C)-triggered type I interferon and inflammatory cytokine production via targeting mitochondrial antiviral signaling protein (MAVS)." in: Oncotarget, Vol. 7, Issue 47, pp. 76667-76683, (2018) (PubMed).

Wu, Lou, Ge, Xiong: "Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos." in: Scientific reports, Vol. 7, Issue 1, pp. 4022, (2018) (PubMed).

Lei, Pan, Li, Zhou, Zhang, He, Peng, Li, Sidhu, Chen, Hua: "H19 regulates the proliferation of bovine male germline stem cells via IGF-1 signaling pathway." in: Journal of cellular physiology, Vol. 234, Issue 1, pp. 915-926, (2018) (PubMed).

Dong, Xu, Yang, Shi, Jiang, Chen, Song, Wang: "Associations of Functional MicroRNA Binding Site Polymorphisms in IL23/Th17 Inflammatory Pathway Genes with Gastric Cancer Risk." in: Mediators of inflammation, Vol. 2017, pp. 6974696, (2018) (PubMed).

Li, Zhu, Yang, Dib-Hajj, Waxman, Yu, Xu, Cheng: "Nav1.7 is phosphorylated by Fyn tyrosine kinase which modulates channel expression and gating in a cell type-dependent manner." in: Molecular pain, Vol. 14, pp. 1744806918782229, (2018) (PubMed).

Zhang, Zhou, Huang, Yu, Zhang, Wang: "Placental mechanism of prenatal nicotine exposure-reduced blood cholesterol levels in female fetal rats." in: Toxicology letters, Vol. 296, pp. 31-38, (2018) (PubMed).

Sheng, Yu, Chen, Wang, Lu: "Infection of grass carp reovirus induced the expressional suppression of pro-viral Fibulin-4 in host cells." in: Fish & shellfish immunology, Vol. 77, pp. 294-297, (2018) (PubMed).

Zhang, Zhang, Deng, Zhang, Liu, Xin, Li, Xu: "Baicalin attenuates non-alcoholic steatohepatitis by suppressing key regulators of lipid metabolism, inflammation and fibrosis in mice." in: Life sciences, Vol. 192, pp. 46-54, (2018) (PubMed).

Liu, Song, Zhao, He, Wang, Chen, Xiang, Yi, Qi, Liu: "Antitumor Activity and Mechanism of a Reverse Transcriptase Inhibitor, Dapivirine, in Glioblastoma." in: Journal of Cancer, Vol. 9, Issue 1, pp. 117-128, (2018) (PubMed).

Liu, Zhang, Yao, Xie, Dai, Zhang, Zhou: "Serum extracellular vesicles promote proliferation of H9C2 cardiomyocytes by increasing miR-17-3p." in: Biochemical and biophysical research communications, Vol. 499, Issue 3, pp. 441-446, (2018) (PubMed).

Li, Zhou, Yang, Li, Zhang, Wang, Jiao: "SGK1 inhibits PM2.5-induced apoptosis and oxidative stress in human lung alveolar epithelial A549 cells." in: Biochemical and biophysical research communications, Vol. 496, Issue 4, pp. 1291-1295, (2018) (PubMed).

Ruan, Zhao, Zhao, Zhang, Shi, Pang: "Knockdown of long noncoding RNA MEG3 impairs VEGF-stimulated endothelial sprouting angiogenesis via modulating VEGFR2 expression in human umbilical vein endothelial cells." in: Gene, Vol. 649, pp. 32-39, (2018) (PubMed).

Qiu, Wu, Meng, Luo, Zhao, Sun, Gao: "GYY4137 protects against myocardial ischemia/reperfusion injury via activation of the PHLPP-1/Akt/Nrf2 signaling pathway in diabetic mice." in: The Journal of surgical research, Vol. 225, pp. 29-39, (2018) (PubMed).

Shen, Zhu, Kang, Tu, Li, Zhang, Qin, Yang, Guan: "Lanosterol Synthase Pathway Alleviates Lens Opacity in Age-Related Cortical Cataract." in: Journal of ophthalmology, Vol. 2018, pp. 4125893, (2018) (PubMed).

Details zu GAPDH

Target: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Andere Bezeichnung: GAPDH (GAPDH Produkte)

Synonyme: G3PD antikoerper, GAPD antikoerper, Gapd antikoerper, BEST:GH12586 antikoerper, CG12055 antikoerper, Dmel\\CG12055 antikoerper, GA3PDH antikoerper, GADPH antikoerper, GAP antikoerper, GAPDH antikoerper, GAPDH I antikoerper, GAPDH-1 antikoerper, GAPDH1 antikoerper, GAPDHI antikoerper, Gapdh antikoerper, Gapdh-1 antikoerper, Gapdh43E antikoerper, gadph antikoerper, gapdh antikoerper, gapdh-1 antikoerper, gh12586 antikoerper, cb609 antikoerper, gapd antikoerper, mg:bb02e05 antikoerper, wu:fb33a10 antikoerper, wu:ft80f05 antikoerper, KNC-NDS6 antikoerper, g3pd antikoerper, G3PDH antikoerper, glyceraldehyde-3-phosphate dehydrogenase antikoerper, Glyceraldehyde 3 phosphate dehydrogenase 1 antikoerper, glyceraldehyde-3-phosphate dehydrogenase S homeolog antikoerper, glyceraldehyde-3-phosphate dehydrogenase, type I antikoerper, olfactory receptor 8K3 antikoerper, GAPDH antikoerper, Gapdh antikoerper, Gapdh1 antikoerper, gapdh antikoerper, gapdh.S antikoerper, gapDH antikoerper, LOC100404960 antikoerper, LOC614985 antikoerper

Hintergrund: This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants.,G3PD,GAPD,HEL-S-162eP,GAPDH,Cancer,Signal Transduction,Endocrine & Metabolism,Carbohydrate metabolism,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,GAPDH

Molekulargewicht: 31 kDa/36 kDa

Gen-ID: 2597

UniProt: P04406