SPHK1 Antikörper (AA 50-384)

Produktnummer ABIN3020648

Produktdetails anti-SPHK1 Antikörper

Target: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Bindungsspezifität: AA 50-384

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPHK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TLMLTERRNH ARELVRSEEL GRWDALVVMS GDGLMHEVVN GLMERPDWET AIQKPLCSLP AGSGNALAAS LNHYAGYEQV TNEDLLTNCT LLLCRRLLSP MNLLSLHTAS GLRLFSVLSL AWGFIADVDL ESEKYRRLGE MRFTLGTFLR LAALRTYRGR LAYLPVGRVG SKTPASPVVV QQGPVDAHLV PLEEPVPSHW TVVPDEDFVL VLALLHSHLG SEMFAAPMGR CAAGVMHLFY VRAGVSRAML LRLFLAMEKG RHMEYECPYL VYVPVVAFRL EPKDGKGVFA VDGELMVSEA VQGQVHPNYF WMVSGCVEPP PSWKPQQMPP PEEPL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-384 of human SPHK1 (NP_001136074.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SPHK1

Target: SPHK1 (Sphingosine Kinase 1 (SPHK1))

Andere Bezeichnung: SPHK1 (SPHK1 Produkte)

Synonyme: CG1747 antikoerper, Dmel\\CG1747 antikoerper, SK1 antikoerper, Sphk1 antikoerper, SPHK1 antikoerper, F18E5.160 antikoerper, F18E5_160 antikoerper, sphingosine kinase 1 antikoerper, SPHK antikoerper, 1110006G24Rik antikoerper, Sk1 antikoerper, Spk1 antikoerper, Sphingosine kinase 1 antikoerper, sphingosine kinase 1 antikoerper, sphingosine kinase 1 L homeolog antikoerper, Sk1 antikoerper, SPHK1 antikoerper, sphk1.L antikoerper, Sphk1 antikoerper

Hintergrund: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.,SPHK1,SPHK,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Kinase,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Angiogenesis,SPHK1

Molekulargewicht: 42 kDa/43 kDa/51 kDa

Gen-ID: 8877

UniProt: Q9NYA1

Pathways: VEGF Signaling