HRAS Antikörper

Produktnummer ABIN302083

Produktdetails anti-HRAS Antikörper

Target: HRAS (HRas proto-oncogene, GTPase (HRAS))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HRAS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: The mouse monoclonal antibody H-RAS-03 reacts with human H-Ras, an ubiquitously expressed 21 kDa intracellular protein. Although reactivity with other species has not been determined, it is probable as the epitope is highly conserved among animals.

Kreuzreaktivität (Details): Human, Other not determined

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: Peptide corresponding to amino acids DIHQYREQIKRVKDSDDC of human H-Ras protein

Klon: H-RAS-03

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western blotting: Recommended dilution: 1-2 μg/mL, reducing conditions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Details zu HRAS

Target: HRAS (HRas proto-oncogene, GTPase (HRAS))

Andere Bezeichnung: H-Ras (HRAS Produkte)

Synonyme: C-BAS/HAS antikoerper, C-H-RAS antikoerper, C-HA-RAS1 antikoerper, CTLO antikoerper, H-RASIDX antikoerper, HAMSV antikoerper, HRAS1 antikoerper, K-RAS antikoerper, N-RAS antikoerper, RASH1 antikoerper, hras antikoerper, zgc:110250 antikoerper, HRAS antikoerper, H-RAS antikoerper, c-H-ras antikoerper, H-Ras antikoerper, K-Ras antikoerper, hras1 antikoerper, rash1 antikoerper, ras antikoerper, N-Ras antikoerper, c-bas/has antikoerper, H-ras antikoerper, Ha-ras antikoerper, Harvey-ras antikoerper, Hras-1 antikoerper, Kras2 antikoerper, c-Ha-ras antikoerper, c-rasHa antikoerper, hrasl antikoerper, zgc:110734 antikoerper, HRas proto-oncogene, GTPase antikoerper, v-Ha-ras Harvey rat sarcoma viral oncogene homolog a antikoerper, neuroblastoma RAS viral (v-ras) oncogene homolog pseudogene antikoerper, Harvey rat sarcoma viral oncogene homolog L homeolog antikoerper, Harvey rat sarcoma viral oncogene homolog antikoerper, Harvey rat sarcoma virus oncogene antikoerper, NRAS proto-oncogene, GTPase antikoerper, -Ha-ras Harvey rat sarcoma viral oncogene homolog b antikoerper, HRAS antikoerper, hrasa antikoerper, LOC733587 antikoerper, Hras antikoerper, hras.L antikoerper, hras antikoerper, NRAS antikoerper, hrasb antikoerper

Hintergrund: HRas proto-oncogene,H-Ras is one of three ubiquitously isoforms of Ras GTPase that operate at the intracellular leaflet of the plasma membrane to regulate multiple signal transduction pathways, such as mitogen-activated protein kinase (MAPK) cascade. H-Ras is anchored to the plasma membrane by farnesyl and two palmityl residues. GTP loading decreases H-Ras affinity for lipid rafts and allows the protein to target to nonraft microdomains, the primary sites of H-Ras signaling. Sos protein and other guanine nucleotide-exchange factors catalyze dissociation of GDP from Ras. Besides its roles in the plasma membrane, active H-Ras also diffuses through the cytoplasm on nanoparticles termed rasosomes, which is dependent on Ras palmitoylation.,Ras-H, HRAS, p21Ras

Gen-ID: 3265

UniProt: P01112

Pathways: p53 Signalweg, MAPK Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Hepatitis C, Autophagie, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling, BCR Signaling