SOD1 Antikörper (AA 1-154)

Produktnummer ABIN3020855

Produktdetails anti-SOD1 Antikörper

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Bindungsspezifität: AA 1-154

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MATKAVCVLK GDGPVQGIIN FEQKESNGPV KVWGSIKGLT EGLHGFHVHE FGDNTAGCTS AGPHFNPLSR KHGGPKDEER HVGDLGNVTA DKDGVADVSI EDSVISLSGD HCIIGRTLVV HEKADDLGKG GNEESTKTGN AGSRLACGVI GIAQ

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-154 of human SOD1 (NP_000445.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-SOD1 Antikörper (ABIN3020855)

Qiu, Wu, Meng, Luo, Zhao, Sun, Gao: "GYY4137 protects against myocardial ischemia/reperfusion injury via activation of the PHLPP-1/Akt/Nrf2 signaling pathway in diabetic mice." in: The Journal of surgical research, Vol. 225, pp. 29-39, (2018) (PubMed).

Lin, Wang, Zou, Sun, Liu, Zhao, Wang, Jin: "The Influenza Virus H5N1 Infection Can Induce ROS Production for Viral Replication and Host Cell Death in A549 Cells Modulated by Human Cu/Zn Superoxide Dismutase (SOD1) Overexpression." in: Viruses, Vol. 8, Issue 1, (2016) (PubMed).

Details zu SOD1

Target: SOD1 (Superoxide Dismutase 1, Soluble (SOD1))

Andere Bezeichnung: SOD1 (SOD1 Produkte)

Synonyme: LOC692639 antikoerper, ALS antikoerper, ALS1 antikoerper, IPOA antikoerper, SOD antikoerper, hSod1 antikoerper, homodimer antikoerper, CG11793 antikoerper, Cu antikoerper, Cu-Zn SOD antikoerper, Cu/Zn SOD antikoerper, Cu/Zn sod antikoerper, Cu/Zn superoxide dismutase antikoerper, Cu/ZnSOD antikoerper, CuSOD antikoerper, CuZn SOD antikoerper, CuZn-SOD antikoerper, CuZn-SOD1 antikoerper, CuZnSOD antikoerper, Cu[2+]/Zn[2+]SOD antikoerper, Dmel\\CG11793 antikoerper, G antikoerper, Mn SOD antikoerper, SOD-1 antikoerper, SOD1 antikoerper, Sod-1 antikoerper, Sod1 antikoerper, To antikoerper, To-1 antikoerper, Zn SOD antikoerper, Zn Sod antikoerper, Zn-SOD antikoerper, ZnSod antikoerper, cSOD antikoerper, cSod antikoerper, dSOD1 antikoerper, l(3)108 antikoerper, l(3)68Af' antikoerper, l(3)G antikoerper, sod antikoerper, sod1 antikoerper, CU/ZN-SOD antikoerper, SODC antikoerper, DKFZP469M1833 antikoerper, B430204E11Rik antikoerper, Cu/Zn-SOD antikoerper, Ipo-1 antikoerper, Ipo1 antikoerper, SOD1L1 antikoerper, XSODB antikoerper, als antikoerper, als1 antikoerper, ipoa antikoerper, sod1-a antikoerper, ZSOD antikoerper, cuzn antikoerper, Cu/Zn superoxide dismutase antikoerper, superoxide dismutase 1 antikoerper, Superoxide dismutase 1 antikoerper, superoxide dismutase 1, soluble antikoerper, superoxide dismutase 1 S homeolog antikoerper, Superoxide dismutase [Cu-Zn] antikoerper, superoxide dismutase 1 L homeolog antikoerper, superoxide dismutase [Cu-Zn]-like antikoerper, superoxide dismutase [Cu-Zn] antikoerper, superoxide dismutase Sod1 antikoerper, SOD antikoerper, SOD1 antikoerper, Sod1 antikoerper, sod1 antikoerper, sod1.S antikoerper, sod-1 antikoerper, sod1.L antikoerper, LOC101451855 antikoerper, LOC101115136 antikoerper

Hintergrund: The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene.,SOD1,ALS,ALS1,HEL-S-44,IPOA,SOD,hSod1,homodimer,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Neuroscience,Neurodegenerative Diseases,SOD1

Molekulargewicht: 15 kDa

Gen-ID: 6647

UniProt: P00441

Pathways: Sensory Perception of Sound, Transition Metal Ion Homeostasis