Estrogen Receptor alpha Antikörper (AA 1-190)

Produktnummer ABIN3020904

Produktdetails anti-Estrogen Receptor alpha Antikörper

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Bindungsspezifität: AA 1-190

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Estrogen Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MTMTLHTKAS GMALLHQIQG NELEPLNRPQ LKIPLERPLG EVYLDSSKPA VYNYPEGAAY EFNAAAAANA QVYGQTGLPY GPGSEAAAFG SNGLGGFPPL NSVSPSPLML LHPPPQLSPF LQPHGQQVPY YLENEPSGYT VREAGPPAFY RPNSDNRRQG GRERLASTND KGSMAMESAK ETRYCAVCND

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human ESRalpha (ESR1) (NP_000116.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:4000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Estrogen Receptor alpha

Target: Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))

Andere Bezeichnung: ESR1 (ESR1 Produkte)

Synonyme: LOC398734 antikoerper, AA420328 antikoerper, AU041214 antikoerper, ER-alpha antikoerper, ER[a] antikoerper, ERa antikoerper, ERalpha antikoerper, ESR antikoerper, Estr antikoerper, Estra antikoerper, Nr3a1 antikoerper, NR3A1 antikoerper, eralpha antikoerper, zfER[a] antikoerper, ER antikoerper, ESRA antikoerper, ESTRR antikoerper, Era antikoerper, akap12 antikoerper, cb27 antikoerper, esr1 antikoerper, fb72g12 antikoerper, id:ibd1202 antikoerper, sb:cb27 antikoerper, si:ch73-192g21.1 antikoerper, wu:fb72g12 antikoerper, wu:fc21c03 antikoerper, Esr antikoerper, RNESTROR antikoerper, ERALPHA antikoerper, er antikoerper, esr antikoerper, nr3a1 antikoerper, XER antikoerper, era antikoerper, esra antikoerper, ERbeta antikoerper, xesr-1 antikoerper, xlERalpha1 antikoerper, xlERalpha2 antikoerper, ESR1 antikoerper, estrogen receptor 1 L homeolog antikoerper, estrogen receptor 1 (alpha) antikoerper, estrogen receptor 1 antikoerper, A kinase (PRKA) anchor protein 12b antikoerper, esr1.L antikoerper, Esr1 antikoerper, ESR1 antikoerper, esr1 antikoerper, akap12b antikoerper

Hintergrund: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined.,ESR1,ER,ESR,ESRA,ESTRR,Era,NR3A1,ER alpha,Epigenetics & Nuclear Signaling,Transcription Factors,Nuclear Receptor Signaling,Signal Transduction,MAPK-Erk Signaling Pathway,ESR1

Molekulargewicht: 35 kDa/47 kDa/53 kDa/66 kDa

Gen-ID: 2099

UniProt: P03372

Pathways: Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly