PLA2G4A Antikörper (AA 1-180)

Produktnummer ABIN3020971

Produktdetails anti-PLA2G4A Antikörper

Target: PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))

Bindungsspezifität: AA 1-180

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLA2G4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MSFIDPYQHI IVEHQYSHKF TVVVLRATKV TKGAFGDMLD TPDPYVELFI STTPDSRKRT RHFNNDINPV WNETFEFILD PNQENVLEIT LMDANYVMDE TLGTATFTVS SMKVGEKKEV PFIFNQVTEM VLEMSLEVCS CPDLRFSMAL CDQEKTFRQQ RKEHIRESMK KLLGPKNSEG

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human PLA2G4A (NP_077734.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PLA2G4A

Target: PLA2G4A (Phospholipase A2, Group IVA (Cytosolic, Calcium-Dependent) (PLA2G4A))

Andere Bezeichnung: PLA2G4A (PLA2G4A Produkte)

Synonyme: PLA2G4 antikoerper, cPLA2-alpha antikoerper, Pla2c antikoerper, Pla2g4 antikoerper, cPLA2 antikoerper, pla2g4 antikoerper, CPLA2 antikoerper, PLA2G4A antikoerper, PLA2 antikoerper, PLA2G1B antikoerper, cPLA2alpha antikoerper, pla2g4a antikoerper, si:dkey-97o5.1 antikoerper, phospholipase A2 group IVA antikoerper, phospholipase A2 group IVA L homeolog antikoerper, phospholipase A2, group IVA (cytosolic, calcium-dependent) antikoerper, phospholipase A2, group IVAb (cytosolic, calcium-dependent) antikoerper, PLA2G4A antikoerper, Pla2g4a antikoerper, pla2g4a.L antikoerper, pla2g4ab antikoerper

Hintergrund: This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles. Alternative splicing results in multiple transcript variants.,PLA2G4A,PLA2G4,cPLA2,cPLA2-alpha,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Phospholipase Signaling Pathway,MAPK-Erk Signaling Pathway,MAPK-P38 Signaling Pathway,Endocrine & Metabolism,Lipid Metabolism,PLA2G4A

Molekulargewicht: 85 kDa

Gen-ID: 5321

UniProt: P47712

Pathways: Inositol Metabolic Process, G-protein mediated Events, VEGF Signaling