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P4HB Antikörper (AA 329-508)

P4HB Reaktivität: Human WB, IHC, IP, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3021094
  • Target Alle P4HB Antikörper anzeigen
    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
    Bindungsspezifität
    • 21
    • 20
    • 15
    • 13
    • 11
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 329-508
    Reaktivität
    • 106
    • 77
    • 67
    • 23
    • 22
    • 21
    • 20
    • 18
    • 18
    • 16
    • 10
    • 10
    • 8
    • 7
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    Human
    Wirt
    • 116
    • 27
    • 2
    Kaninchen
    Klonalität
    • 110
    • 35
    Polyklonal
    Konjugat
    • 61
    • 16
    • 15
    • 9
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser P4HB Antikörper ist unkonjugiert
    Applikation
    • 111
    • 66
    • 43
    • 43
    • 43
    • 37
    • 18
    • 15
    • 14
    • 13
    • 13
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
    Sequenz
    PESEELTAER ITEFCHRFLE GKIKPHLMSQ ELPEDWDKQP VKVLVGKNFE DVAFDEKKNV FVEFYAPWCG HCKQLAPIWD KLGETYKDHE NIVIAKMDST ANEVEAVKVH SFPTLKFFPA SADRTVIDYN GERTLDGFKK FLESGGQDGA GDDDDLEDLE EAEEPDMEED DDQKAVKDEL
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 329-508 of human P4HB (NP_000909.2).
    Isotyp
    IgG
    Top Product
    Discover our top product P4HB Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:20 - 1:100,IP,1:50 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    P4HB (Prolyl 4-Hydroxylase, beta Polypeptide (P4HB))
    Andere Bezeichnung
    P4HB (P4HB Produkte)
    Synonyme
    DSI antikoerper, ERBA2L antikoerper, GIT antikoerper, P4Hbeta antikoerper, PDI antikoerper, PDIA1 antikoerper, PHDB antikoerper, PO4DB antikoerper, PO4HB antikoerper, PROHB antikoerper, PDA2 antikoerper, PDIP antikoerper, PDIR antikoerper, ERp59 antikoerper, Pdia1 antikoerper, Thbp antikoerper, p55 antikoerper, XPDIp antikoerper, pdi antikoerper, 1810041F13Rik antikoerper, AI661267 antikoerper, Pdip antikoerper, Pdipl antikoerper, p58 antikoerper, prolyl 4-hydroxylase subunit beta antikoerper, protein disulfide isomerase family A member 2 antikoerper, prolyl 4-hydroxylase, beta polypeptide antikoerper, protein disulfide isomerase family A member 2 L homeolog antikoerper, protein disulfide isomerase associated 2 antikoerper, prolyl 4-hydroxylase subunit beta L homeolog antikoerper, protein disulfide-isomerase antikoerper, P4HB antikoerper, PDIA2 antikoerper, P4hb antikoerper, pdia2.L antikoerper, Pdia2 antikoerper, p4hb.L antikoerper, LOC8281065 antikoerper
    Hintergrund
    This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex.,P4HB,CLCRP1,DSI,ERBA2L,GIT,P4Hbeta,PDI,PDIA1,PHDB,PO4DB,PO4HB,PROHB,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,Endocrine & Metabolism,Lipid Metabolism,P4HB
    Molekulargewicht
    57 kDa
    Gen-ID
    5034
    UniProt
    P07237
    Pathways
    Maintenance of Protein Location, Cell RedoxHomeostasis, Lipid Metabolism
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