WASP Antikörper (AA 60-250)

Produktnummer ABIN3021208

Produktdetails anti-WASP Antikörper

Target: WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

Bindungsspezifität: AA 60-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WASP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GAEHWTKEHC GAVCFVKDNP QKSYFIRLYG LQAGRLLWEQ ELYSQLVYST PTPFFHTFAG DDCQAGLNFA DEDEAQAFRA LVQEKIQKRN QRQSGDRRQL PPPPTPANEE RRGGLPPLPL HPGGDQGGPP VGPLSLGLAT VDIQNPDITS SRYRGLPAPG PSPADKKRSG KKKISKADIG APSGFKHVSH V

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-250 of human WASPP (NP_000368.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu WASP

Target: WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))

Andere Bezeichnung: WAS (WAS Produkte)

Synonyme: IMD2 antikoerper, SCNX antikoerper, THC antikoerper, THC1 antikoerper, WASP antikoerper, U42471 antikoerper, WASp antikoerper, Wasp antikoerper, imd2 antikoerper, thc antikoerper, thc1 antikoerper, was antikoerper, wasp antikoerper, wu:fk81c08 antikoerper, zgc:64164 antikoerper, Wiskott-Aldrich syndrome antikoerper, neural Wiskott-Aldrich syndrome protein antikoerper, wiskott-aldrich syndrome protein antikoerper, Wiskott-Aldrich syndrome L homeolog antikoerper, Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b antikoerper, WAS antikoerper, LOC5578888 antikoerper, CpipJ_CPIJ006699 antikoerper, Was antikoerper, was.L antikoerper, wasb antikoerper

Hintergrund: The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.,WAS,IMD2,SCNX,THC,THC1,WASP,WASPA,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Actins,Immunology & Inflammation,T Cell Receptor Signaling Pathway,WAS

Molekulargewicht: 52 kDa

Gen-ID: 7454

UniProt: P42768