Cyclin H Antikörper (AA 1-323)

Produktnummer ABIN3021259

Produktdetails anti-Cyclin H Antikörper

Target: Cyclin H (CCNH)

Bindungsspezifität: AA 1-323

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Sequenz: MYHNSSQKRH WTFSSEEQLA RLRADANRKF RCKAVANGKV LPNDPVFLEP HEEMTLCKYY EKRLLEFCSV FKPAMPRSVV GTACMYFKRF YLNNSVMEYH PRIIMLTCAF LACKVDEFNV SSPQFVGNLR ESPLGQEKAL EQILEYELLL IQQLNFHLIV HNPYRPFEGF LIDLKTRYPI LENPEILRKT ADDFLNRIAL TDAYLLYTPS QIALTAILSS ASRAGITMES YLSESLMLKE NRTCLSQLLD IMKSMRNLVK KYEPPRSEEV AVLKQKLERC HSAELALNVI TKKRKGYEDD DYVSKKSKHE EEEWTDDDLV ESL

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-323 of human Cyclin H (NP_001230.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IP,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Cyclin H

Target: Cyclin H (CCNH)

Andere Bezeichnung: CCNH (CCNH Produkte)

Synonyme: zgc:114132 antikoerper, cak antikoerper, p34 antikoerper, p37 antikoerper, Cych antikoerper, ACYPI004637 antikoerper, ccnh antikoerper, Cyclin-H antikoerper, 142767_at antikoerper, CG7405 antikoerper, Dmel\\CG7405 antikoerper, CAK antikoerper, 6330408H09Rik antikoerper, AI661354 antikoerper, AV102684 antikoerper, AW538719 antikoerper, ccnh-A antikoerper, cyclin H antikoerper, cyclin-H antikoerper, Cyclin H antikoerper, CYclin H antikoerper, cyclin H L homeolog antikoerper, CCNH antikoerper, ccnh antikoerper, LOC5577539 antikoerper, Cych antikoerper, CycH antikoerper, cyh-1 antikoerper, Ccnh antikoerper, ccnh.L antikoerper

Hintergrund: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants.,CCNH,CAK,CycH,p34,p37,cyclin-H,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Cell Cycle,Cyclins,CCNH

Molekulargewicht: 37 kDa

Gen-ID: 902

UniProt: P51946

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, M Phase