PRMT1 Antikörper (AA 20-353)

Produktnummer ABIN3021312

Produktdetails anti-PRMT1 Antikörper

Target: PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Bindungsspezifität: AA 20-353

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRMT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: SSEKPNAEDM TSKDYYFDSY AHFGIHEEML KDEVRTLTYR NSMFHNRHLF KDKVVLDVGS GTGILCMFAA KAGARKVIGI ECSSISDYAV KIVKANKLDH VVTIIKGKVE EVELPVEKVD IIISEWMGYC LFYESMLNTV LYARDKWLAP DGLIFPDRAT LYVTAIEDRQ YKDYKIHWWE NVYGFDMSCI KDVAIKEPLV DVVDPKQLVT NACLIKEVDI YTVKVEDLTF TSPFCLQVKR NDYVHALVAY FNIEFTRCHK RTGFSTSPES PYTHWKQTVF YMEDYLTVKT GEEIFGTIGM RPNAKNNRDL DFTIDLDFKG QLCELSCSTD YRMR

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-353 of human PRMT1 (NP_938074.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu PRMT1

Target: PRMT1 (Protein Arginine Methyltransferase 1 (PRMT1))

Andere Bezeichnung: PRMT1 (PRMT1 Produkte)

Hintergrund: This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.,PRMT1,ANM1,HCP1,HRMT1L2,IR1B4,Epigenetics & Nuclear Signaling,Chromatin Modifying Enzymes,Methylation,Nuclear Receptor Signaling,Cancer,Tumor suppressors,p53 pathway,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,PRMT1

Molekulargewicht: 39 kDa/40 kDa/41 kDa

Gen-ID: 3276

UniProt: Q99873