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PPP3CA Antikörper (AA 1-511)
PPP3CA
Reaktivität: Human
WB, IF
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN6214918
Produktdetails anti-PPP3CA Antikörper
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Target
Alle PPP3CA Antikörper anzeigen
PPP3CA
(Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))
Bindungsspezifität
Alle Epitope für PPP3CA Antikörper
AA 1-511
Reaktivität
Alle Reaktivitäten für PPP3CA Antikörper
Human
Wirt
Alle Wirte für PPP3CA Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für PPP3CA Antikörper
Polyklonal
Konjugat
Alle Konjugate für PPP3CA Antikörper
Dieser PPP3CA Antikörper ist unkonjugiert
Applikation
Alle Applikationen für PPP3CA Antikörper
Western Blotting (WB), Immunofluorescence (IF)
Sequenz
MSEPKAIDPK LSTTDRVVKA VPFPPSHRLT AKEVFDNDGK PRVDILKAHL MKEGRLEESV ALRIITEGAS ILRQEKNLLD IDAPVTVCGD IHGQFFDLMK LFEVGGSPAN TRYLFLGDYV DRGYFSIECV LYLWALKILY PKTLFLLRGN HECRHLTEYF TFKQECKIKY SERVYDACMD AFDCLPLAAL MNQQFLCVHG GLSPEINTLD DIRKLDRFKE PPAYGPMCDI LWSDPLEDFG NEKTQEHFTH NTVRGCSYFY SYPAVCEFLQ HNNLLSILRA HEAQDAGYRM YRKSQTTGFP SLITIFSAPN YLDVYNNKAA VLKYENNVMN IRQFNCSPHP YWLPNFMDVF TWSLPFVGEK VTEMLVNVLN ICSDDELGSE EDGFDGATAA ARKEVIRNKI RAIGKMARVF SVLREESESV LTLKGLTPTG MLPSGVLSGG KQTLQSAIKG FSPQHKITSF EEAKGLDRIN ERMPPRRDAM PSDANLNSIN KALTSETNGT DSNGSNSSNI Q
Kreuzreaktivität
Human, Maus
Produktmerkmale
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-511 of human Calcineurin A (NP_001124163.1).
Isotyp
IgG
Top Product
Discover our top product PPP3CA Primärantikörper
Alternativen
(anzeigen)
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (Middle Region) antibody
PPP3CA
Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Pferd, Zebrafisch (Danio rerio), Meerschweinchen
WB
Wirt: Kaninchen
Polyclonal
unconjugated
anti-Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA) (N-Term) antibody
PPP3CA
Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Pferd, Schwein, Zebrafisch (Danio rerio)
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
WB,1:500 - 1:2000,IF,1:50 - 1:200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid freeze / thaw cycles
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Referenzen für anti-PPP3CA Antikörper (ABIN6214918)
(ausblenden)
Chen, Wang, Long, Jia, Zhang, Deng, Li, Han, Wang : "Fasting-induced hormonal regulation of lysosomal function. " in: Cell research , Vol. 27 , Issue 6 , pp. 748-763 , (2018 ) (PubMed ).
Details zu PPP3CA
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Target
PPP3CA
(Protein Phosphatase 3, Catalytic Subunit, alpha Isoform (PPP3CA))
Andere Bezeichnung
PPP3CA (PPP3CA Produkte )
Synonyme
CALN antikoerper, CALNA antikoerper, CALNA1 antikoerper, CCN1 antikoerper, CNA1 antikoerper, PPP2B antikoerper, 2900074D19Rik antikoerper, AI841391 antikoerper, AW413465 antikoerper, CN antikoerper, Caln antikoerper, Calna antikoerper, CnA antikoerper, Calna1 antikoerper, calcineurin antikoerper, caln antikoerper, calna antikoerper, calna1 antikoerper, ccn1 antikoerper, cna1 antikoerper, ppp2b antikoerper, fj46e08 antikoerper, si:dkeyp-79c2.2 antikoerper, wu:fj46e08 antikoerper, ppp3ca antikoerper, protein phosphatase 3 catalytic subunit alpha antikoerper, protein phosphatase 3, catalytic subunit, alpha isoform antikoerper, protein phosphatase 3, catalytic subunit, alpha isozyme antikoerper, protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) antikoerper, protein phosphatase 3, catalytic subunit, alpha isozyme L homeolog antikoerper, serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform antikoerper, PPP3CA antikoerper, Ppp3ca antikoerper, ppp3ca antikoerper, ppp3ca.L antikoerper, LOC100205420 antikoerper
Hintergrund
Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+-mediated signals. Many of the substrates contain a PxIxIT motif and/or a LxVP motif. In response to increased Ca(2+ levels, dephosphorylates and activates phosphatase SSH1 which results in cofilin dephosphorylation. In response to increased Ca(2+ levels following mitochondrial depolarization, dephosphorylates DNM1L inducing DNM1L translocation to the mitochondrion. Dephosphorylates heat shock protein HSPB1 (By similarity. Dephosphorylates and activates transcription factor NFATC1. In response to increased Ca(2+ levels, regulates NFAT-mediated transcription probably by dephosphorylating NFAT and promoting its nuclear translocation. Dephosphorylates and inactivates transcription factor ELK1. Dephosphorylates DARPP32. May dephosphorylate CRTC2 at 'Ser-171' resulting in CRTC2 dissociation from 14-3-3 proteins. Dephosphorylates transcription factor TFEB at 'Ser-211' following Coxsackievirus B3 infection, promoting nuclear translocation.,PPP3CA,CALN,CALNA,CALNA1,CCN1,CNA1,PPP2B,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Cytoskeleton,Actins,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,Neuroscience,Calcium Signaling,Neurodegenerative Diseases,PPP3CA
Molekulargewicht
31 kDa/51 kDa/52 kDa/57 kDa/58 kDa
Gen-ID
5530
UniProt
Q08209
Pathways
RTK Signalweg , WNT Signalweg , Fc-epsilon Rezeptor Signalübertragung , Negative Regulation of Hormone Secretion , Carbohydrate Homeostasis , Synaptic Membrane , Skeletal Muscle Fiber Development , Protein targeting to Nucleus , VEGF Signaling , BCR Signaling
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