TTR Antikörper (AA 21-147)

Produktnummer ABIN3021474

Produktdetails anti-TTR Antikörper

Target: TTR (Transthyretin (TTR))

Bindungsspezifität: AA 21-147

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: GPTGTGESKC PLMVKVLDAV RGSPAINVAV HVFRKAADDT WEPFASGKTS ESGELHGLTT EEEFVEGIYK VEIDTKSYWK ALGISPFHEH AEVVFTANDS GPRRYTIAAL LSPYSYSTTA VVTNPKE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-147 of human TTR (NP_000362.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-TTR Antikörper (ABIN3021474)

Tesch, Abdirama, Grießbach, Brand, Goerlich, Humrich, Bacher, Hiepe, Riemekasten, Enghard: "Identification and characterization of antigen-specific CD4+ T cells targeting renally expressed antigens in human lupus nephritis with two independent methods." in: Scientific reports, Vol. 10, Issue 1, pp. 21312, (2020) (PubMed).

Details zu TTR

Target: TTR (Transthyretin (TTR))

Andere Bezeichnung: TTR (TTR Produkte)

Synonyme: zgc:103583 antikoerper, TTR antikoerper, LOC100226992 antikoerper, CTS antikoerper, CTS1 antikoerper, HsT2651 antikoerper, PALB antikoerper, TBPA antikoerper, AA408768 antikoerper, AI787086 antikoerper, D17860 antikoerper, prealbumin antikoerper, Lr1 antikoerper, Tbpa antikoerper, Prealbumin antikoerper, xTTR antikoerper, transthyretin (prealbumin, amyloidosis type I) antikoerper, transthyretin antikoerper, Transthyretin antikoerper, transthyretin (prealbumin, amyloidosis type 1) antikoerper, transthyretin-like antikoerper, transthyretin L homeolog antikoerper, ttr antikoerper, TTR antikoerper, vpb38 antikoerper, MRAD2831_RS38185 antikoerper, Caci_4246 antikoerper, LOC100226992 antikoerper, Ttr antikoerper, ttr.L antikoerper

Hintergrund: This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.,TTR,CTS,CTS1,HEL111,HsT2651,PALB,TBPA,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Cardiovascular,Blood,Serum Proteins,TTR

Molekulargewicht: 15 kDa

Gen-ID: 7276

UniProt: P02766

Pathways: Hormone Transport