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MSH2 Antikörper (AA 1-300)

Name: MSH2 Antikörper (AA 1-300)
Brand: antibodies-online
SKU: ABIN3021477
Price: 722.37 EUR
Availability: InStock

MSH2 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated

Western Blotting (WB) image for anti-Mismatch Repair Protein 2 (MSH2) (AA 1-300) antibody (ABIN3021477) (MSH2 Antikörper (AA 1-300))

Immunohistochemistry of paraffin-embedded Human esophageal using MSH2 antibody at dilution of 1:100 (x400 lens). (MSH2 Antikörper (AA 1-300))

IHC

Immunofluorescence analysis of HeLa cell using MSH2 antibody. (MSH2 Antikörper (AA 1-300))

Immunohistochemistry of paraffin-embedded Human colon using MSH2 antibody at dilution of 1:100 (x400 lens). (MSH2 Antikörper (AA 1-300))

IHC

Immunohistochemistry of paraffin-embedded human kidney cancer using MSH2 antibody at dilution of 1:200 (x400 lens). (MSH2 Antikörper (AA 1-300))

IHC

Western blot analysis of extracts of various cell lines, using MSH2 antibody. (MSH2 Antikörper (AA 1-300))

Immunoprecipitation analysis of 150ug extracts of A549 cells using 3ug MSH2 antibody. (MSH2 Antikörper (AA 1-300))

7 Abbildungen

Produktnummer ABIN3021477

Datenblatt (PDF)

Target Alle MSH2 Antikörper anzeigen

MSH2 (Mismatch Repair Protein 2 (MSH2))
Bindungsspezifität
15

8

8

7

7

6

6

4

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 1-300
Reaktivität
79

41

20

6

6

6

4

3

3

3

3

2

2

1

1

1
Human
Wirt
75

18

1
Kaninchen
Passende Sekundärantikörper
Klonalität
71

24
Polyklonal
Konjugat
60

5

5

4

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser MSH2 Antikörper ist unkonjugiert
Applikation
57

37

27

22

22

14

13

12

11

8

7

4

3

2

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Sequenz

MAVQPKETLQ LESAAEVGFV RFFQGMPEKP TTTVRLFDRG DFYTAHGEDA LLAAREVFKT QGVIKYMGPA GAKNLQSVVL SKMNFESFVK DLLLVRQYRV EVYKNRAGNK ASKENDWYLA YKASPGNLSQ FEDILFGNND MSASIGVVGV KMSAVDGQRQ VGVGYVDSIQ RKLGLCEFPD NDQFSNLEAL LIQIGPKECV LPGGETAGDM GKLRQIIQRG GILITERKKA DFSTKDIYQD LNRLLKGKKG EQMNSAVLPE MENQVAVSSL SAVIKFLELL SDDSNFGQFE LTTFDFSQYM

Kreuzreaktivität

Human, Maus, Ratte

Produktmerkmale

Polyclonal Antibodies

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human MSH2 (NP_000242.1).

Isotyp

IgG

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Applikationshinweise

WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:20 - 1:50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid freeze / thaw cycles

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C. Avoid freeze / thaw cycles.
Target

MSH2 (Mismatch Repair Protein 2 (MSH2))

Andere Bezeichnung

MSH2 (MSH2 Produkte)

Synonyme

COCA1 antikoerper, FCC1 antikoerper, HNPCC antikoerper, HNPCC1 antikoerper, LCFS2 antikoerper, AI788990 antikoerper, wu:fc06b02 antikoerper, wu:fc13e09 antikoerper, zgc:55333 antikoerper, ATMSH2 antikoerper, MUTS homolog 2 antikoerper, msh2 antikoerper, mutS homolog 2 antikoerper, mutS homolog 2 (E. coli) antikoerper, MUTS homolog 2 antikoerper, mutS homolog 2 L homeolog antikoerper, MutS protein homolog 2 antikoerper, MSH2 antikoerper, Msh2 antikoerper, msh2 antikoerper, msh2.L antikoerper

Hintergrund

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.,MSH2,COCA1,FCC1,HNPCC,HNPCC1,LCFS2,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Tumor suppressors,Cell Biology & Developmental Biology,Apoptosis,MSH2

Molekulargewicht

97 kDa/104 kDa

Gen-ID

4436

UniProt

P43246

Pathways

DNA Reparatur, Production of Molecular Mediator of Immune Response