Arrestin 3 Antikörper (AA 300-400)
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- Target Alle Arrestin 3 (ARRB2) Antikörper anzeigen
- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
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Bindungsspezifität
- AA 300-400
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Arrestin 3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Sequenz
- NLASSTIVKE GANKEVLGIL VSYRVKVKLV VSRGGDVSVE LPFVLMHPKP HDHIPLPRPQ SAAPETDVPV DTNLIEFDTN YATDDDIVFE DFARLRLKGM K
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 300-400 of human ARRB2 (NP_004304.1).
- Isotyp
- IgG
- Top Product
- Discover our top product ARRB2 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid freeze / thaw cycles
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))
- Andere Bezeichnung
- ARRB2 (ARRB2 Produkte)
- Synonyme
- ARRB2 antikoerper, arb2 antikoerper, arr2 antikoerper, arrestin antikoerper, barr2 antikoerper, betaarr2 antikoerper, ARB2 antikoerper, ARR2 antikoerper, BARR2 antikoerper, BARRES antikoerper, AI326910 antikoerper, AW122872 antikoerper, arrb2 antikoerper, zgc:64007 antikoerper, arrestin beta 2 antikoerper, arrestin, beta 2 antikoerper, arrestin beta 2 L homeolog antikoerper, arrestin, beta 2b antikoerper, ARRB2 antikoerper, arrb2 antikoerper, Arrb2 antikoerper, arrb2.L antikoerper, arrb2b antikoerper
- Hintergrund
- Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.,ARRB2,ARB2,ARR2,BARR2,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Notch Signaling Pathway,ARRB2
- Molekulargewicht
- 44 kDa/45 kDa/46 kDa/47 kDa/48 kDa
- Gen-ID
- 409
- UniProt
- P32121
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling
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