F11R Antikörper (AA 30-238)

Produktnummer ABIN3021823

Produktdetails anti-F11R Antikörper

Target: F11R (F11 Receptor (F11R))

Bindungsspezifität: AA 30-238

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser F11R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: TVHSSEPEVR IPENNPVKLS CAYSGFSSPR VEWKFDQGDT TRLVCYNNKI TASYEDRVTF LPTGITFKSV TREDTGTYTC MVSEEGGNSY GEVKVKLIVL VPPSKPTVNI PSSATIGNRA VLTCSEQDGS PPSEYTWFKD GIVMPTNPKS TRAFSNSSYV LNPTTGELVF DPLSASDTGE YSCEARNGYG TPMTSNAVRM EAVERNVGV

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-238 of human F11R (NP_058642.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-F11R Antikörper (ABIN3021823)

Knowlton, Fernández de Castro, Ashbrook, Gestaut, Zamora, Bauer, Forrest, Frydman, Risco, Dermody: "The TRiC chaperonin controls reovirus replication through outer-capsid folding." in: Nature microbiology, Vol. 3, Issue 4, pp. 481-493, (2018) (PubMed).

Details zu F11R

Target: F11R (F11 Receptor (F11R))

Andere Bezeichnung: F11R (F11R Produkte)

Synonyme: CD321 antikoerper, JAM antikoerper, JAM1 antikoerper, JAMA antikoerper, JCAM antikoerper, KAT antikoerper, PAM-1 antikoerper, 9130004G24 antikoerper, AA638916 antikoerper, ESTM33 antikoerper, JAM-1 antikoerper, JAM-A antikoerper, Jcam antikoerper, Jcam1 antikoerper, Ly106 antikoerper, Jam1 antikoerper, F11 receptor antikoerper, F11R antikoerper, F11r antikoerper

Hintergrund: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.,F11R,CD321,JAM,JAM1,JAMA,JCAM,KAT,PAM-1,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Tight Junctions,Cytoskeleton,Immunology & Inflammation,CD markers,Cardiovascular,Blood,F11R

Molekulargewicht: 27 kDa/32 kDa

Gen-ID: 50848

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization