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CBS Antikörper (AA 252-551)

CBS Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3021959
  • Target Alle CBS Antikörper anzeigen
    CBS (Cystathionine-beta-Synthase (CBS))
    Bindungsspezifität
    • 15
    • 9
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 252-551
    Reaktivität
    • 54
    • 41
    • 12
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 65
    • 9
    Kaninchen
    Klonalität
    • 59
    • 15
    Polyklonal
    Konjugat
    • 39
    • 6
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CBS Antikörper ist unkonjugiert
    Applikation
    • 56
    • 31
    • 17
    • 14
    • 14
    • 14
    • 13
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Sequenz
    VASVGTGGTI TGIARKLKEK CPGCRIIGVD PEGSILAEPE ELNQTEQTTY EVEGIGYDFI PTVLDRTVVD KWFKSNDEEA FTFARMLIAQ EGLLCGGSAG STVAVAVKAA QELQEGQRCV VILPDSVRNY MTKFLSDRWM LQKGFLKEED LTEKKPWWWH LRVQELGLSA PLTVLPTITC GHTIEILREK GFDQAPVVDE AGVILGMVTL GNMLSSLLAG KVQPSDQVGK VIYKQFKQIR LTDTLGRLSH ILEMDHFALV VHEQIQYHST GKSSQRQMVF GVVTAIDLLN FVAAQERDQK
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 252-551 of human CBS (NP_000062.1).
    Isotyp
    IgG
    Top Product
    Discover our top product CBS Primärantikörper
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Niu, Wang, Qian, Wang, Wu, Chen, Yan: "Allosteric control of human cystathionine β-synthase activity by a redox active disulfide bond." in: The Journal of biological chemistry, Vol. 293, Issue 7, pp. 2523-2533, (2018) (PubMed).

    Seale, Ha, Hashimoto, Berry: "Relationship between selenoprotein P and selenocysteine lyase: Insights into selenium metabolism." in: Free radical biology & medicine, Vol. 127, pp. 182-189, (2018) (PubMed).

  • Target
    CBS (Cystathionine-beta-Synthase (CBS))
    Andere Bezeichnung
    CBS (CBS Produkte)
    Synonyme
    hip4 antikoerper, GB12529 antikoerper, CBS antikoerper, DDBDRAFT_0189727 antikoerper, DDBDRAFT_0191292 antikoerper, DDB_0189727 antikoerper, DDB_0191292 antikoerper, cbs antikoerper, AI047524 antikoerper, AI303044 antikoerper, HIP4 antikoerper, cb442 antikoerper, wu:fb37g05 antikoerper, wu:fm61c07 antikoerper, wu:fq06c06 antikoerper, zgc:113704 antikoerper, cystathionine-beta-synthase L homeolog antikoerper, cystathionine-beta-synthase antikoerper, cystathionine beta-synthase antikoerper, cystathionine beta-synthase CBS antikoerper, cystathionine beta synthase antikoerper, cystathionine-beta-synthase S homeolog antikoerper, cystathionine-beta-synthase b antikoerper, cbs.L antikoerper, cbs antikoerper, Cbs antikoerper, CBS antikoerper, CNA06170 antikoerper, Tb11.02.5400 antikoerper, cysB antikoerper, LOC100635325 antikoerper, cbs.S antikoerper, cbsb antikoerper
    Hintergrund
    The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. This gene is a major contributor to cellular hydrogen sulfide production. Multiple alternatively spliced transcript variants have been found for this gene.,CBS,HIP4,Cancer,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,CBS
    Molekulargewicht
    60 kDa/61 kDa
    Gen-ID
    875
    UniProt
    P35520
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