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RENT1/UPF1 Antikörper (AA 270-370)

UPF1 Reaktivität: Human WB, IF, IP Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3022069
  • Target Alle RENT1/UPF1 (UPF1) Antikörper anzeigen
    RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
    Bindungsspezifität
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 270-370
    Reaktivität
    • 53
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 47
    • 3
    • 3
    Kaninchen
    Klonalität
    • 46
    • 7
    Polyklonal
    Konjugat
    • 29
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RENT1/UPF1 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 16
    • 14
    • 14
    • 8
    • 8
    • 7
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    Sequenz
    KENPSATLED LEKPGVDEEP QHVLLRYEDA YQYQNIFGPL VKLEADYDKK LKESQTQDNI TVRWDLGLNK KRIAYFTLPK TDSDMRLMQG DEICLRYKGD L
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    A synthetic peptide corresponding to a sequence within amino acids 270-370 of human UPF1/RENT1 (NP_002902.2).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    RENT1/UPF1 (UPF1) (UPF1 Regulator of Nonsense Transcripts Homolog (UPF1))
    Andere Bezeichnung
    UPF1 (UPF1 Produkte)
    Hintergrund
    This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants.,UPF1,HUPF1,NORF1,RENT1,pNORF1,smg-2,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,UPF1
    Molekulargewicht
    123 kDa/124 kDa
    Gen-ID
    5976
    UniProt
    Q92900
    Pathways
    SARS-CoV-2 Protein Interaktom
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