Muscarinic Acetylcholine Receptor M2 Antikörper (AA 208-388)

Produktnummer ABIN3022149

Produktdetails anti-Muscarinic Acetylcholine Receptor M2 Antikörper

Target: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Bindungsspezifität: AA 208-388

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Muscarinic Acetylcholine Receptor M2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HISRASKSRI KKDKKEPVAN QDPVSPSLVQ GRIVKPNNNN MPSSDDGLEH NKIQNGKAPR DPVTENCVQG EEKESSNDST SVSAVASNMR DDEITQDENT VSTSLGHSKD ENSKQTCIRI GTKTPKSDSC TPTNTTVEVV GSSGQNGDEK QNIVARKIVK MTKQPAKKKP PPSREKKVTR T

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 208-388 of human Muscarinic AChR M2 (ACM2) (NP_001006629.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Muscarinic Acetylcholine Receptor M2

Target: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Andere Bezeichnung: CHRM2 (CHRM2 Produkte)

Synonyme: HM2 antikoerper, AChR-M2 antikoerper, Chrm-2 antikoerper, M2 antikoerper, chrm2 antikoerper, Acm2 antikoerper, GPM2 antikoerper, cholinergic receptor muscarinic 2 antikoerper, cholinergic receptor, muscarinic 2, cardiac antikoerper, cholinergic receptor, muscarinic 2a antikoerper, cholinergic receptor, muscarinic 2 antikoerper, CHRM2 antikoerper, Chrm2 antikoerper, chrm2a antikoerper

Hintergrund: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.,CHRM2,HM2,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRM2

Molekulargewicht: 51 kDa

Gen-ID: 1129

UniProt: P08172