AT3 antikoerper, AT3D antikoerper, ATIII antikoerper, THPH7 antikoerper, SERPINC1 antikoerper, DKFZp470C1733 antikoerper, AI114908 antikoerper, At-3 antikoerper, At3 antikoerper, ANTITHROMBIN, AT-III antikoerper, AT-III antikoerper, serpin family C member 1 antikoerper, antithrombin-III antikoerper, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 antikoerper, SERPINC1 antikoerper, CpipJ_CPIJ000472 antikoerper, CpipJ_CPIJ013111 antikoerper, Serpinc1 antikoerper
Hintergrund
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.,SERPINC1,AT3,AT3D,ATIII,THPH7,Stem Cells,Cardiovascular,Blood,Coagulation,Serum Proteins,SERPINC1