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BTK Antikörper (AA 30-240)

BTK Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3022171
  • Target Alle BTK Antikörper anzeigen
    BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
    Bindungsspezifität
    • 35
    • 16
    • 15
    • 14
    • 9
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 30-240
    Reaktivität
    • 126
    • 79
    • 62
    • 12
    • 6
    • 4
    • 2
    Human
    Wirt
    • 141
    • 16
    Kaninchen
    Klonalität
    • 128
    • 30
    Polyklonal
    Konjugat
    • 67
    • 12
    • 9
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Dieser BTK Antikörper ist unkonjugiert
    Applikation
    • 104
    • 59
    • 40
    • 40
    • 37
    • 19
    • 18
    • 17
    • 10
    • 10
    • 10
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    FLLTVHKLSY YEYDFERGRR GSKKGSIDVE KITCVETVVP EKNPPPERQI PRRGEESSEM EQISIIERFP YPFQVVYDEG PLYVFSPTEE LRKRWIHQLK NVIRYNSDLV QKYHPCFWID GQYLCCSQTA KNAMGCQILE NRNGSLKPGS SHRKTKKPLP PTPEEDQILK KPLPPEPAAA PVSTSELKKV VALYDYMPMN ANDLQLRKGD E
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Aufreinigung
    Affinity purification
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 30-240 of human BTK (NP_000052.1).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:500 - 1:2000,IHC,1:50 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    BTK (Bruton Agammaglobulinemia tyrosine Kinase (BTK))
    Andere Bezeichnung
    BTK (BTK Produkte)
    Hintergrund
    The protein encoded by this gene plays a crucial role in B-cell development. Mutations in this gene cause X-linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.,AGMX1,AT,ATK,BPK,IMD1,PSCTK1,XLA,BTK,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,B Cell Receptor Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,BTK
    Molekulargewicht
    76 kDa/79 kDa
    Gen-ID
    695
    UniProt
    Q06187
    Pathways
    Fc-epsilon Rezeptor Signalübertragung, Hormone Transport, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, BCR Signaling
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