THRB Antikörper (AA 1-250)
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- Target Alle THRB Antikörper anzeigen
- THRB (Thyroid Hormone Receptor, beta (THRB))
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Bindungsspezifität
- AA 1-250
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser THRB Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Sequenz
- MTPNSMTENG LTAWDKPKHC PDREHDWKLV GMSEACLHRK SHSERRSTLK NEQSSPHLIQ TTWTSSIFHL DHDDVNDQSV SSAQTFQTEE KKCKGYIPSY LDKDELCVVC GDKATGYHYR CITCEGCKGF FRRTIQKNLH PSYSCKYEGK CVIDKVTRNQ CQECRFKKCI YVGMATDLVL DDSKRLAKRK LIEENREKRR REELQKSIGH KPEPTDEEWE LIKTVTEAHV ATNAQGSHWK QKRKFLPEDI
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human THRB (NP_000452.2).
- Isotyp
- IgG
- Top Product
- Discover our top product THRB Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid freeze / thaw cycles
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Target
- THRB (Thyroid Hormone Receptor, beta (THRB))
- Andere Bezeichnung
- THRB (THRB Produkte)
- Hintergrund
- The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene.,THRB,C-ERBA-2,C-ERBA-BETA,ERBA2,GRTH,NR1A2,PRTH,THR1,THRB1,THRB2,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Neuroscience,THRB
- Molekulargewicht
- 52 kDa/54 kDa
- Gen-ID
- 7068
- UniProt
- P10828
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Sensory Perception of Sound
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