Renin Antikörper (AA 24-160)

Produktnummer ABIN3022188

Produktdetails anti-Renin Antikörper

Target: Renin (REN)

Bindungsspezifität: AA 24-160

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Renin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: LPTDTTTFKR IFLKRMPSIR ESLKERGVDM ARLGPEWSQP MKRLTLGNTT SSVILTNYMD TQYYGEIGIG TPPQTFKVVF DTGSSNVWVP SSKCSRLYTA CVYHKLFDAS DSSSYKHNGT ELTLRYSTGT VSGFLSQ

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-160 of human Renin (NP_000528.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:100 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Renin

Target: Renin (REN)

Andere Bezeichnung: REN (REN Produkte)

Synonyme: HNFJ2 antikoerper, RATRENAA antikoerper, RENAA antikoerper, Ren1 antikoerper, D19352 antikoerper, Ren antikoerper, Ren-1 antikoerper, Ren-A antikoerper, Ren1c antikoerper, Ren1d antikoerper, Rn-1 antikoerper, Rnr antikoerper, renin antikoerper, renin 1 structural antikoerper, REN antikoerper, Ren antikoerper, Ren1 antikoerper, ren antikoerper

Hintergrund: Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.,REN,HNFJ2,renin,Renin,Cardiovascular,Blood,Blood Pressure regulation,REN

Molekulargewicht: 44 kDa/45 kDa

Gen-ID: 5972

UniProt: P00797

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour