Dihydrofolate Reductase Antikörper (AA 1-187)

Produktnummer ABIN3022228

Produktdetails anti-Dihydrofolate Reductase Antikörper

Target: Dihydrofolate Reductase (DHFR)

Bindungsspezifität: AA 1-187

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dihydrofolate Reductase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: MVGSLNCIVA VSQNMGIGKN GDLPWPPLRN EFRYFQRMTT TSSVEGKQNL VIMGKKTWFS IPEKNRPLKG RINLVLSREL KEPPQGAHFL SRSLDDALKL TEQPELANKV DMVWIVGGSS VYKEAMNHPG HLKLFVTRIM QDFESDTFFP EIDLEKYKLL PEYPGVLSDV QEEKGIKYKF EVYEKND

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-187 of human DHFR (NP_000782.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Dihydrofolate Reductase

Target: Dihydrofolate Reductase (DHFR)

Andere Bezeichnung: DHFR (DHFR Produkte)

Synonyme: DHFR antikoerper, F10_orf160 antikoerper, ECK0049 antikoerper, JW0047 antikoerper, tmrA antikoerper, cb595 antikoerper, zgc:86637 antikoerper, DDBDRAFT_0187132 antikoerper, DDBDRAFT_0230113 antikoerper, DDB_0187132 antikoerper, DDB_0230113 antikoerper, CG14887 antikoerper, Dmel\\CG14887 antikoerper, dhfr antikoerper, DHFRP1 antikoerper, DYR antikoerper, 8430436I03Rik antikoerper, AA607882 antikoerper, AI662710 antikoerper, AW555094 antikoerper, Dhfr1 antikoerper, confers resistance to sulfonamides antikoerper, dihydrofolate reductase antikoerper, dihydrofolate reductase DhfR antikoerper, Dihydrofolate reductase antikoerper, dhfr antikoerper, DHFR antikoerper, dhfR antikoerper, folA antikoerper, dfrA antikoerper, LOC707382 antikoerper, CNJ01940 antikoerper, DDB_G0286755 antikoerper, Dhfr antikoerper, Mesil_0096 antikoerper, Arch_0408 antikoerper, Fbal_3367 antikoerper, Ilyop_0482 antikoerper, Lbys_2007 antikoerper, Riean_0733 antikoerper, Mrub_1855 antikoerper, Poras_0766 antikoerper, Halhy_3552 antikoerper, Mesop_3614 antikoerper, LOC609048 antikoerper

Hintergrund: Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene.,DHFR,DHFRP1,DYR,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Endocrine & Metabolism,Amino acid metabolism,Nucleotide metabolism,DHFR

Molekulargewicht: 15 kDa/21 kDa

Gen-ID: 1719

UniProt: P00374

Pathways: Mitotic G1-G1/S Phases