DPYD Antikörper (AA 1-173)

Produktnummer ABIN3022259

Produktdetails anti-DPYD Antikörper

Target: DPYD (Dihydropyrimidine Dehydrogenase (DPYD))

Bindungsspezifität: AA 1-173

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPYD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MAPVLSKDSA DIESILALNP RTQTHATLCS TSAKKLDKKH WKRNPDKNCF NCEKLENNFD DIKHTTLGER GALREAMRCL KCADAPCQKS CPTNLDIKSF ITSIANKNYY GAAKMIFSDN PLGLTCGMVC PTSDLCVGGC NLYATEEGPI NIGGLQQFAT ETLILAFSLM NHL

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-173 of human DPYD (NP_001153773.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DPYD

Target: DPYD (Dihydropyrimidine Dehydrogenase (DPYD))

Andere Bezeichnung: DPYD (DPYD Produkte)

Synonyme: DPYD antikoerper, dpyd antikoerper, zgc:77205 antikoerper, AI315208 antikoerper, DPD antikoerper, E330028L06Rik antikoerper, DHP antikoerper, DHPDHASE antikoerper, dhp antikoerper, dhpdhase antikoerper, dpd antikoerper, 14.t00017 antikoerper, DDBDRAFT_0189681 antikoerper, DDBDRAFT_0231100 antikoerper, DDB_0189681 antikoerper, DDB_0231100 antikoerper, dpyda antikoerper, zgc:153505 antikoerper, dihydropyrimidine dehydrogenase antikoerper, dihydropyrimidine dehydrogenase b antikoerper, dihydropyrimidine dehydrogenase L homeolog antikoerper, dihydropyrimidine dehydrogenase [NADP(+)] antikoerper, dihydropyrimidine dehydrogenase a, tandem duplicate 1 antikoerper, DPYD antikoerper, Dpyd antikoerper, dpydb antikoerper, dpyd.L antikoerper, EHI_012980 antikoerper, LOC5573038 antikoerper, EDI_044620 antikoerper, pyd1 antikoerper, dpyda.1 antikoerper

Hintergrund: The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene.,DPYD,DHP,DHPDHASE,DPD,Signal Transduction,Endocrine & Metabolism,Amino acid metabolism,DPYD

Molekulargewicht: 18 kDa/111 kDa

Gen-ID: 1806

UniProt: Q12882

Pathways: Ribonucleoside Biosynthetic Process