SELPLG Antikörper (AA 40-280)

Produktnummer ABIN3022340

Produktdetails anti-SELPLG Antikörper

Target: SELPLG (Selectin P Ligand (SELPLG))

Bindungsspezifität: AA 40-280

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SELPLG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RRQATEYEYL DYDFLPETEP PEMLRNSTDT TPLTGPGTPE STTVEPAARR STGLDAGGAV TELTTELANM GNLSTDSAAM EIQTTQPAAT EAQTTPLAAT EAQTTRLTAT EAQTTPLAAT EAQTTPPAAT EAQTTQPTGL EAQTTAPAAM EAQTTAPAAM EAQTTPPAAM EAQTTQTTAM EAQTTAPEAT EAQTTQPTAT EAQTTPLAAM EALSTEPSAT EALSMEPTTK RGLFIPFSVS S

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-280 of human SELPLG (NP_002997.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SELPLG

Target: SELPLG (Selectin P Ligand (SELPLG))

Andere Bezeichnung: SELPLG (SELPLG Produkte)

Synonyme: CD162 antikoerper, CLA antikoerper, PSGL-1 antikoerper, PSGL1 antikoerper, SELPLG antikoerper, SELPG antikoerper, Psgl-1 antikoerper, Psgl1 antikoerper, Selp1 antikoerper, Selpl antikoerper, selectin P ligand antikoerper, selectin, platelet (p-selectin) ligand antikoerper, clasper antikoerper, SELPLG antikoerper, Selplg antikoerper, cla antikoerper

Hintergrund: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.,SELPLG,CD162,CLA,PSGL-1,PSGL1,Cell Biology & Developmental Biology,Cell Adhesion,Cell Adhesion Molecules,Immunology & Inflammation,CD markers,Cardiovascular,SELPLG

Molekulargewicht: 43 kDa/44 kDa

Gen-ID: 6404

UniProt: Q14242