KNG1 Antikörper (AA 148-427)

Produktnummer ABIN3022364

Produktdetails anti-KNG1 Antikörper

Target: KNG1 (Kininogen 1 (KNG1))

Bindungsspezifität: AA 148-427

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KNG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: PISTQSPDLE PILRHGIQYF NNNTQHSSLF MLNEVKRAQR QVVAGLNFRI TYSIVQTNCS KENFLFLTPD CKSLWNGDTG ECTDNAYIDI QLRIASFSQN CDIYPGKDFV QPPTKICVGC PRDIPTNSPE LEETLTHTIT KLNAENNATF YFKIDNVKKA RVQVVAGKKY FIDFVARETT CSKESNEELT ESCETKKLGQ SLDCNAEVYV VPWEKKIYPT VNCQPLGMIS LMKRPPGFSP FRSSRIGEIK EETTSHLRSC EYKGRPPKAG AEPASEREVS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 148-427 of human Kininogen 1 (Kininogen 1 (KNG1)) (NP_000884.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu KNG1

Target: KNG1 (Kininogen 1 (KNG1))

Andere Bezeichnung: KNG1 (KNG1 Produkte)

Synonyme: BDK antikoerper, BK antikoerper, KNG antikoerper, Kng antikoerper, KNG2 antikoerper, fb64g01 antikoerper, wu:fb64g01 antikoerper, zgc:103569 antikoerper, kininogen antikoerper, bdk antikoerper, kng antikoerper, KNG1 antikoerper, IHRP antikoerper, KINKG antikoerper, KINKH antikoerper, Kng1 antikoerper, Kngk antikoerper, kininogen 1 antikoerper, kininogen 1 L homeolog antikoerper, inter-alpha-trypsin inhibitor heavy chain family member 4 antikoerper, kininogen 2-like 1 antikoerper, KNG1 antikoerper, Kng1 antikoerper, kng1 antikoerper, kng1.L antikoerper, ITIH4 antikoerper, Kng2l1 antikoerper

Hintergrund: This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.,KNG1,BDK,BK,KNG,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Apoptosis,Cardiovascular,Blood,KNG1

Molekulargewicht: 43 kDa/47 kDa/71 kDa

Gen-ID: 3827

UniProt: P01042

Pathways: ACE Inhibitor Pathway, Glycosaminoglycan Metabolic Process