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POLB Antikörper (AA 1-335)

POLB Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3022385
  • Target Alle POLB Antikörper anzeigen
    POLB (Polymerase (DNA Directed), beta (POLB))
    Bindungsspezifität
    • 15
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-335
    Reaktivität
    • 43
    • 41
    • 27
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 53
    • 3
    Kaninchen
    Klonalität
    • 46
    • 9
    Polyklonal
    Konjugat
    • 24
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser POLB Antikörper ist unkonjugiert
    Applikation
    • 34
    • 17
    • 15
    • 14
    • 13
    • 8
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Sequenz
    MSKRKAPQET LNGGITDMLT ELANFEKNVS QAIHKYNAYR KAASVIAKYP HKIKSGAEAK KLPGVGTKIA EKIDEFLATG KLRKLEKIRQ DDTSSSINFL TRVSGIGPSA ARKFVDEGIK TLEDLRKNED KLNHHQRIGL KYFGDFEKRI PREEMLQMQD IVLNEVKKVD SEYIATVCGS FRRGAESSGD MDVLLTHPSF TSESTKQPKL LHQVVEQLQK VHFITDTLSK GETKFMGVCQ LPSKNDEKEY PHRRIDIRLI PKDQYYCGVL YFTGSDIFNK NMRAHALEKG FTINEYTIRP LGVTGVAGEP LPVDSEKDIF DYIQWKYREP KDRSE
    Kreuzreaktivität
    Human, Maus
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-335 of human DNA Polymerase beta (NP_002681.1).
    Isotyp
    IgG
  • Applikationshinweise
    WB,1:200 - 1:1000,IHC,1:50 - 1:200,IF,1:20 - 1:200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid freeze / thaw cycles
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Xu, Zhang, Zhang, Meng, Zhang, Jiang, Xu, Van Meter, Seluanov, Gorbunova, Mao: "SIRT6 rescues the age related decline in base excision repair in a PARP1-dependent manner." in: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 2, pp. 269-76, (2015) (PubMed).

  • Target
    POLB (Polymerase (DNA Directed), beta (POLB))
    Andere Bezeichnung
    POLB (POLB Produkte)
    Synonyme
    wu:fa97a05 antikoerper, zgc:109924 antikoerper, POLB antikoerper, DDBDRAFT_0186152 antikoerper, DDBDRAFT_0215784 antikoerper, DDBDRAFT_0232376 antikoerper, DDB_0186152 antikoerper, DDB_0215784 antikoerper, DDB_0232376 antikoerper, A430088C08Rik antikoerper, polymerase (DNA directed), beta antikoerper, DNA polymerase beta antikoerper, DNA polymerase X family protein antikoerper, polymerase (DNA directed), beta S homeolog antikoerper, polb antikoerper, POLB antikoerper, polB antikoerper, polb.S antikoerper, Polb antikoerper
    Hintergrund
    The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date.,POLB,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cell Biology & Developmental Biology,Apoptosis,POLB
    Molekulargewicht
    38 kDa
    Gen-ID
    5423
    UniProt
    P06746
    Pathways
    DNA Reparatur
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